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benighted

Definition: (adjective) Being in a state of moral or intellectual darkness; unenlightened.
Synonyms:dark
Usage:They felt it might be a being partially benighted in the vale of ignorance, but it could not be one who would willingly devote his rich natural gifts to the purposes of wanton treachery. Discuss.
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Necrotizing Fasciitis

Necrotizing fasciitis is a rare infection of the deeper layers of skin and subcutaneous tissue caused by what are commonly known as "flesh-eating bacteria." One of the fastest-spreading infections known, it develops at trauma sites and destroys both skin and muscle. Since the bacteria react slowly to intravenous antibiotics, treatment is often immediately undertaken along with surgical intervention if the condition is even suspected. Who are a few well-known victims of the infection? More... Discuss
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Appetite Hormone Linked to Alzheimer's

Leptin, a hormone produced by fat cells that helps regulate appetite, has long been touted as a possible treatment for obesity. Now, researchers believe that it may also reduce the risk of developing Alzheimer's disease. A 12-year study of 200 volunteers found that those with the lowest levels of the hormone were more likely to develop the disease than those with the highest levels. Furthermore, research on mice found that those that received doses of leptin were more adept at navigating a maze. More... Discuss
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The Simpsons Debuts (1989)

One of the most popular animated TV shows in US history, The Simpsons has earned its spot in pop culture history through its parodies of the "Middle American" lifestyle. The show, created by Matt Groening, is a spin-off of a series of animated shorts originally aired on The Tracey Ullman Show and is currently both the longest-running American sitcom and the longest-running American animated program. Which state's Springfield hosted the premiere of The Simpsons Movie in 2006? More... Discuss
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John Kennedy Toole (1937)

Toole was an American novelist from New Orleans, Louisiana, best known for his novel A Confederacy of Dunces. His mental health began to deteriorate after his manuscript—which Toole considered a masterpiece—was rejected by a publisher, and he committed suicide in 1969. Years after his death, Toole's mother brought the manuscript to novelist Walker Percy, who ushered the book into print. In 1981, Toole was posthumously awarded the Pulitzer Prize. What is Toole's only other novel? More... Discuss
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Books are good enough in their own way, but they are a poor substitute for life.

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