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A steroid hormone, C21H30O3, secreted by the adrenal cortex or produced synthetically and formerly used to treat adrenal insufficiency.


(diːˌɒksɪˌkɔːtɪkəʊˈstɪərəʊn) or


(Biochemistry) a corticosteroid hormone important in maintaining sodium and water balance in the body


(diˌɒk sɪˌkɔr tɪˈkɒs təˌroʊn, -ˌkoʊ stəˈroʊn)

a steroid hormone, C21H30O3, secreted by the adrenal cortex, related to corticosterone, and involved in water and electrolyte balance.


n. desoxicorticosterona, hormona producida en la corteza de las glándulas suprarrenales de efecto marcado en el metabolismo del agua y los electrólitos.
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In patients with this disorder, the steroid precursors are converted to progesterone and then to products with mineralocorticoid activity such as 11-deoxycorticosterone and corticosterone.
We measured 15 adrenal steroids simultaneously by LCMS/MS, including aldosterone, cortisol, 18-oxocortisol, 18-hydroxycortisol, cortisone, 11-deoxycortisol, 21deoxycortisol, corticosterone, 11-deoxycorticosterone, progesterone, 17-hydroxyprogesterone, pregnenolone, androstenedione, dehydroepiandrosterone (DHEA), and DHEA-sulfate (DHEA-S).
71) However, both forms of CYP11B1 were capable of catalyzing aldosterone formation as well as the 11[beta]-and 18-hydroxylation of 11-deoxycorticosterone, although the intensities of those enzymatic activities of the two forms were slightly different.
11-beta hydroxylase mediates the final step in the glucocorticoid pathway and the conversion of 11-deoxycorticosterone (DOC) into corticosterone.
All core clinical biochemistry and hormonal tests were performed at Royal Hospital, Oman, using Architect 8000c and Architect 2000i, respectively, with Automated Processing System (Abbott, USA); and 17[alpha]-hydroxyprogesterone, renin and aldosterone were performed by ELISA (DRG, USA); while 11-deoxycortisol, 11-deoxycorticosterone, corticosterone, androstenedione and ACTH were performed at Laboratoroire Cerba (France).
21 (alpha) OHD deficiency leading to failure of conversion of progesterone to 11-deoxycorticosterone may result in aldosterone deficiency which is called "salt losing type" of CAH.
Plasma 11-deoxycorticosterone (DOC) and mineralocorticoid receptor testicular expression during rainbow trout, Oncorhynchus mykiss, spermiation: implication with 17 alpha, 20 betadihydroxyprogesterone on the milt fluidity?