isotretinoin

(redirected from 13-cis-retinoic acid)
Also found in: Medical, Acronyms.

i·so·tre·ti·noin

 (ī′sō-trĕt′n-oin′)
n.
A synthetic isomer of retinoic acid that inhibits sebaceous gland secretion and is used in the treatment of severe nodular acne. It can cause birth defects if taken during pregnancy.

[iso- + tretinoin, retinoic acid (t(rans)- + retino(ic acid) + -in).]

isotretinoin

(ˌaɪsəʊtrəˈtɪnəʊɪn)
n
(Pharmacology) a drug related to vitamin A, used to treat severe acne that has failed to respond to other treatment
Translations

isotretinoin

n isotretinoína
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References in periodicals archive ?
18) indicated, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-2 (IL-2), and 13-cis-retinoic acid (RA), for the treatment of pediatric patients with high-risk neuroblastoma who achieve at least a partial response to prior first-line multiagent, multimodality therapy.
It is essential that drugs like 13-cis-retinoic acid are used as effectively as possible to further improve the treatment of childhood cancer.
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Anderson Cancer Center in Houston first reported using the synthetic substance, called 13-cis-retinoic acid, to treat leukoplakia - whitish patches of skin in the mouth that can turn malignant.
6M Ask for IP related to Inkjet Digital Printing and a $3M Ask for IP related to therapeutic uses of 13-Cis-Retinoic Acid, are available for immediate purchase and represent a small sampling of the quality and diversity of activity recently initiated on P/B-A.
Joe's health began to improve when he was put forward for a clinical trial run by the Northern Institute for Cancer Research at Newcastle University which investigated the treatment of neuroblastoma with the drug 13-cis-retinoic acid, which plays a key role in preventing the cancer from returning following surgery, chemotherapy and radiotherapy.