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isotretinoin
(redirected from 13-cis-retinoic acid)

    Also found in: Medical, Acronyms, Wikipedia 0.01 sec.
i·so·tre·ti·noin  (s-trtn-oin)
n.
A synthetic retinoid, C20H28O2, that inhibits sebaceous gland secretion and is used in the treatment of severe forms of acne.
[iso- + tretinoin, retinoic acid (t(rans)- + retino(ic acid) + -in).]
isotretinoin [ˌaɪsəʊtrəˈtɪnəʊɪn]
n
(Medicine / Pharmacology) a drug related to vitamin A, used to treat severe acne that has failed to respond to other treatment
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Effects of 13-cis-retinoic acid, all-trans-retinoic acid, and acitretin on the proliferation, lipid synthesis and keratin expression of cultured human sebocytes in vitro.
Beneficial actions of citrus polymethoxy flavonoids in treating acne by Sato, Takashi; Ito, Akira / Clinical Dermatology
A vitamin A derivative called 13-cis-retinoic acid is effective in the childhood nervous system cancer called neuroblastoma, which strikes 500 people in the United States each year.
BEATING CANCER; ONSLAUGHT OF EXPERIMENTAL THERAPIES HERALDS ERA OF ... by Daily News (Los Angeles, CA)
The team designed a clinical trial in which 53 people with leukoplakia received a very large dose of 13-cis-retinoic acid for three months.
Vitamin A-like drug may ward off cancers by Fackelmann, Kathy A. / Science News
 
 
 
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