dopa

(redirected from 3,4-dihydroxyphenylalanine)
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do·pa

 (dō′pə)
n.
An amino acid, C9H11NO4, that occurs widely in animals and plants. In humans and other mammals, it is formed in the liver from tyrosine and converted to dopamine in the brain.

[d(ihydr)o(xy)p(henyl)a(lanine).]

dopa

(ˈdəʊpə)
n
(Biochemistry) See L-dopa

do•pa

(ˈdoʊ pə)

n.
an amino acid, C9H11NO4, formed from tyrosine in the liver during melanin and epinephrine biosynthesis. Compare L-dopa.
[< German Dopa (1917), contraction of 3, 4-Dioxyphenylanin]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.dopa - amino acid that is formed in the liver and converted into dopamine in the brain
amino acid, aminoalkanoic acid - organic compounds containing an amino group and a carboxylic acid group; "proteins are composed of various proportions of about 20 common amino acids"
Bendopa, Brocadopa, Larodopa, L-dopa, levodopa - the levorotatory form of dopa (trade names Bendopa and Brocadopa and Larodopa); as a drug it is used to treat Parkinson's disease
References in periodicals archive ?
Hydroquinone (HQ), a phenolic compound, blocks the conversion of 3,4-dihydroxyphenylalanine (DOPA) to melanin through inhibiting tyrosinase7 and reduces dyschromia through melanocyte downregulation, prevention of melanosome production, and reduction of melanin transfer to keratinocytes.
Tyrosinase is rate-limiting enzyme controlling the production of melanin and catalyze the conversion of L-tyrosine supplied from the blood to 3,4-dihydroxyphenylalanine, then to dopaquinone.
Notewor-thily, tyrosine residues of both Pc-1 and Pc-2 are post-translationally modified into 3,4-dihydroxyphenylalanine (DOPA) by the addition of a hydroxyl group (Waite et al.
These dopamine-deficient mice required daily administration of 3,4-dihydroxyphenylalanine (Ldopa) for survival beyond two to three weeks of age.

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