thioguanine

(redirected from 6-TG)
Also found in: Thesaurus, Medical, Acronyms.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.thioguanine - an antineoplastic drug used to treat acute leukemias
antineoplastic, antineoplastic drug, cancer drug - any of several drugs that control or kill neoplastic cells; used in chemotherapy to kill cancer cells; all have unpleasant side effects that may include nausea and vomiting and hair loss and suppression of bone marrow function
References in periodicals archive ?
Separation of 6-TG and 6-MMP derivative was achieved with an 8-min isocratic elution with 95% mobile phase A-5% mobile phase B at a flow rate of 0.
We determined intra- and interday imprecision by analyzing low, medium, and high concentrations of 6-TG and 6-MMP added to erythrocyte hemolysates.
This was followed by hydrolysis (100 [degrees]C for 45 min) of the 6-TGNs in the separated supernatant to release the 6-TG.
For chromatographic separation of the free 6-TG after both sample preparation procedures described above, we used a modification (7) of the Lennard chromatographic method (21).
The free bases, 6-TG and 6-MP, liberated from the respective nucleoside and nucleotide moiety by acid hydrolysis, were analyzed on an octadecylsilane column after liquid-liquid extraction with dichloromethane.
6-TG and Me6-MP derivative liberated from the nucleotide moiety were analyzed by a reversed-phase HPLC method.