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mercaptopurine
(redirected from 6-mercaptopurine)

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
mer·cap·to·pu·rine  (mr-kpt-pyrn)
n.
A purine analogue, C5H4N4S, that acts as an antimetabolite by interfering with purine synthesis, used primarily in the treatment of acute leukemia.

mercaptopurine [məˌkæptəʊˈpjʊəriːn]
n
(Medicine / Pharmacology) a drug used in the treatment of leukaemia. Formula: C5H4N4S
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.mercaptopurine - a drug (trade name Purinethol) that interferes with the metabolism of purine and is used to treat acute lymphocytic leukemia
antimetabolite - an antineoplastic drug that inhibits the utilization of a metabolite


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During maintenance therapy with 6-mercaptopurine and Methotrexate she developed bicytopenia (macrocytic anemia and thrombocytopenia) one year after the diagnosis of the malignant lymphoma.
ABSTRACT Background: Genetic polymorphisms in thiopurine methyltransferase (TPMT) influence the metabolism of azathioprine (AZA) and 6-mercaptopurine (6-MP) in patients with inflammatory bowel disease (IBD).
Since performing surgery and increasing the 6-mercaptopurine dosage, we have been able to lengthen the interval between the patient's laser treatments to every 9 to 12 months.
 
 
 
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