ACTH


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Related to ACTH: cortisol, ACTH stimulation test

ACTH

 (ā′sē′tē′āch′)
n.
A hormone produced by the anterior lobe of the pituitary gland that stimulates the secretion of cortisol and other hormones by the adrenal cortex. Also called adrenocorticotropin, corticotropin.

[a(dreno)c(ortico)t(ropic) h(ormone).]

ACTH

n
(Biochemistry) adrenocorticotrophic hormone; a polypeptide hormone, secreted by the anterior lobe of the pituitary gland, that stimulates growth of the adrenal gland and the synthesis and secretion of corticosteroids. It is used in treating rheumatoid arthritis, allergic and skin diseases, and many other disorders. Also called: corticotrophin

ACTH

a hormone of the anterior pituitary that stimulates the production of steroids in the cortex of the adrenal glands.
Also called adrenocorticotropic hormone, adrenocorticotropin.
[1940–45; a(dreno)c(ortico)t(ropic)h(ormone)]

ACTH

(ā′sē′tē-āch′)
Short for adrenocorticotropic hormone. A hormone secreted by a lobe of the pituitary gland. It stimulates the adrenal glands to produce cortisone and related hormones.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.ACTH - a hormone produced by the anterior pituitary gland that stimulates the adrenal cortexACTH - a hormone produced by the anterior pituitary gland that stimulates the adrenal cortex
endocrine, hormone, internal secretion - the secretion of an endocrine gland that is transmitted by the blood to the tissue on which it has a specific effect
Translations

ACTH

abbr adrenocorticotropic hormone. V. hormone.
References in periodicals archive ?
Finding the source of ectopic ACTH production can be challenging, as these tumors are typically small and radiographically covert on routine CT imaging (10).
Drugs profile discussed in this report include ALD-1613, AT-814, ATR-101, DG-3173, ISIS-GCCRRx, ketoconazole, LCI-699, mifepristone, MPP-482, pasireotide LAR, Peptides to Antagonize ACTH Receptor for Cushing's Syndrome, Small Molecule to Antagonize Melanocortin Receptor 2 for Cushing's Disease, Small Molecule to Inhibit CYP11B1 for Cushing's Disease and Subclinical Hypercortisolism, Small Molecules to Antagonize Steroidogenic Factor-1 for Endometriosis, Cancer and Cushing's Disease, Small Molecules to Inhibit Cortisol for Metabolic Disorders, Small Molecules to Modulate Cryptochrome for Metabolic and CNS Disorders.
4) "[T]he large doses of ACTH send you off in a rocket and are scarcely less disagreeable than the disease," O'Connor wrote in a letter.
In this case the underlying pathophysiology is further subdivided into adrenocorticotropic hormone (ACTH) dependent or ACTH independent.
One drawback, however, is that current ACTH ELISA kits on the market are 4-hour tests.
Increase of Plasma ACTH concentrations in the stress state can also act as a stimulus and cause the secretion of leptin [20].
The plasma ACTH level increased to normal by 4 months after surgery (Table 2).
On laboratory examination, the patient showed decreased ACTH (2.
Further workup showed elevated serum cortisol and serum ACTH levels.
Here, we describe a case not only with high plasma ACTH level also with symptoms of both hypercortisolism and hypocortisolism together under the conventional therapy and which was successfully treated by mimicking physiological diurnal cortisol secretion of the patient.
The TSST has been shown to evoke a robust and predictable response curve for subjective distress, heart rate, blood pressure, cortisol, and ACTH (Kirschbaum et al.