Among the chemotherapeutic agents, epidermal growth factor receptor inhibitors are associated with intensely itchy papulopustular rash or acneiform eruptions
that occur mainly on the seborrheic areas such as the face, scalp and chest.
Furunculosis, lichen planus, and reactive perforating collagenosis, lichen sclerosus, solar degeneration and acneiform eruptions
are less common.
This number might be an overestimation since all reactions to medications were considered to be true emergencies, but reactions such as fixed drug eruption and acneiform eruptions
are not really considered as such.
The patients' ages, duration of the disease, family history, presence of oral ulcers, genital ulcers, erythema nodosum, acneiform eruptions
, epididymitis, arthralgia and arthritis, and vascular, pulmonary, gastrointestinal, neurological, and ophthalmic involvement were recorded.
In Pudukadan et al  study, the mean absolute eosinophil count was abnormal in most eruptions, with values more than 500 cells/mm3, except in cases of acneiform eruptions
, urticaria/angioedema, and eczematoid, lichenoid and fixed drug eruption patients.
6 Since anticonvulsants lead to a lot of dermal complications such as rash, hypersensitivity syndrome, alopecia, pseudolymphomatous lesions, gingival hyperplasia, erythema multiforme, acneiform eruptions
, Vasculitis, Drug lupus, and Stevens-Johnson syndrome.
The aim of this study was to evaluate the adverse skin reactions, mainly acneiform eruptions
caused by these chemotherapeutic agents.
in infants and toddlers can occasionally be associated with scarring or with other significant disorders that may be life-threatening.