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a.1.Of or pertaining to aconite.
2.(Chem.) Pert. to or designating a crystalline tribasic acid, C6H6O6, obtained from aconite and other plants. It is a carboxyl derivative of itaconic acid. Both the natural forma from plants and the form prepared chemically have the trans-configuration. It is used in the manufacture of itaconic acid (propylene dicarboxylic acid).
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Increased activity of the tricarboxylic acid cycle because of an altered metabolism in cartilage and chondrocytes was hypothesized due to an elevated expression of aconitic acid, isocitric acid, and citric acid in the urine of OA patients.
Table 1: Frequency of Increased * Urinary Excretion of Krebs Cycle Metabolites In Chronic Inflammatory Disorders Krebs Cycle Metabolites 2004 n = 236 2015 n = 315 Citric acid 194 315 Succinic acid 40 55 Aconitic acid 24 45 Fumaric acid 2 2 2-oxo-glutaric acid 1 2 * Levels of Krebs metabolites measured in mmol/mol creatinine.
Louis, USA), and aconitic acid (ACA) (Aldrich, Milwaukee, USA) as monomer, N,N'-methylenebisacrylamide (Bis) (Merck, Schuchardt, Germany) as crosslinkers, ammonium persulfate (APS) (Merck, Schuchardt, Germany) as redox initiator and N, N, N', N'-tetramethyl ethylene diamine (TEMED) (Sigma, St.