In this study, we reported a new method by 'gently' digesting the fat tissue to produce viable adipocytes
, progenitors, and stromal stem cells using collagenase I digestion and centrifugation.
The findings showed that cinnamaldehyde, an essential oil that gives cinnamon its flavor,improves metabolic health by acting directly on fat cells, or adipocytes
, inducing them to start burning energy through a process called thermogenesis.
Wu and her colleagues tested human adipocytes
from volunteers representing a range of ages, ethnicities and body mass indices.
Besides osteoblasts, mesenchymal stem cells can also differentiate into the chondrocyte cells that make cartilage, the myocyte cells that help form muscles and the adipocytes
, or fat cells.
In addition, previous studies have shown that lipophilic statins, such as simvastatin, reduce the GLUT4 protein levels in adipocytes
, whereas hydrophilic statins (pravastatin) do not.
In AT development, formation of new adipocytes
via differentiation of progenitor cells is intimately coupled to the ensuing expansion of adipocytes
(hypertrophy) via lipid accumulation; the enzymes and regulatory proteins responsible for lipid droplet (LD) formation are also markers of differentiation.
In mature adipocytes
, glucose transporter type 4 (Glut-4) is highly expressed and responds to insulin to lower blood glucose .
2+] levels were determined in pre-adipocytes
of 3T3-L1 cells.
The subcutaneous adipose tissue (SAT) has been found to be associated with higher Acrp30 production compared to the visceral fat component of adipocytes
The cells appear to display high viability and they differentiated into metabolically active brown adipocytes
as shown by UCP-1 expression.
While all adipocytes
are mesenchymal in origin, an appreciable diversity arises during the process of differentiation; in fact BAT, in some way, has more in common with muscle cells of mesenchymal origin than with WAT [19-23].
The aim of this study was to determine if the cross-sex hormonal replacement modifies antioxidant enzyme activities in retroperitoneal fat adipocytes