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Alpha and beta thalassemia are distinguished by the amount of the minor adult hemoglobin Hb [A.
People with thalassemia or sickle cell anemia have damaged adult hemoglobin, the vital molecule that picks up oxygen in the lungs and transports it around the body.
Fetal and adult hemoglobin are two different molecular forms of the essential oxygen-carrying molecule in red blood cells.
Vrste hemoglobina u eritrocitima odraslih osoba Hemoglobin species Globin Vrsta hemoglobina Globin Adult hemoglobin A/Adultni [[alpha].
The thalassemia syndromes are a heterogeneous autosomal recessive group of disorders caused by inherited mutations that decrease the synthesis of adult hemoglobin HbA4.
Back to the 1980s, baboons, a nonhuman primate model, have already been used for the study of fetal and adult hemoglobin synthesis during fetal development [40, 41].
When patients with SCD undergo this transition, their inherited gene mutation distorts adult hemoglobin, forcing red blood cells to assume a sickled shape.
Normal adult hemoglobin is Hemoglobin A, consisting of two alpha chains and two beta chains.
Since fetal hemoglobin is more apt to ferric state compared to adult hemoglobin (Hb A2), newborn infants have a greater tendency to methemoglobinemia.
In the article the researchers said they are one step closer to developing a feasible cure or long-term treatment options for patients with SCD, which is caused by a single DNA letter change in the gene for adult hemoglobin, the principle protein in red blood cells needed to carry oxygen.
Example 2: Fetal hemoglobin is replaced by adult hemoglobin (1) during the first 6 months of life.
In the fetus and newborn, however, fetal hemoglobin permits greater delivery of oxygen to tissues than adult hemoglobin does.

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