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affinity
(redirected from Affinity maturation)

   Also found in: Medical, Legal, Encyclopedia, Wikipedia, Hutchinson 0.05 sec.
af·fin·i·ty  (-fn-t)
n. pl. af·fin·i·ties
1. A natural attraction, liking, or feeling of kinship.
2. Relationship by marriage.
3. An inherent similarity between persons or things. See Synonyms at likeness.
4. Biology A relationship or resemblance in structure between species that suggests a common origin.
5. Immunology The attraction between an antigen and an antibody.
6. Chemistry An attraction or force between particles that causes them to combine.

[Middle English affinite, from Old French afinite, from Latin affnits, from affnis, related by marriage; see affined.]
Usage Note: In the sense of "attraction," affinity may be followed by of, between, or with. Thus one may speak of the close affinity of James and Samuel, or of the affinity between James and Samuel, or of James's affinity with Samuel. In its chemical use affinity is generally followed by for: a dye with an affinity for synthetic fabrics. · One might want to avoid using affinity as a simple synonym for liking since 62 percent of the Usage Panel rejects the example Her affinity for living in California led her to reject a chance to return to New York. Nevertheless, the more sophisticated tone inherent in this use of the word can lend an archness to certain contexts, as when Barbara Tuchman writes of Kaiser Wilhelm's "affinity for coarse physical jokes practiced upon his courtiers." This may be why 65 percent of the Usage Panel approved of this quotation when it was presented as an example.

affinity
Noun
pl -ties
1. a feeling of closeness to and understanding of a person
2. a close similarity in appearance, structure, or quality
3. a chemical attraction [Latin affinis bordering on, related]

affinity  (-fn-t)
1. A relationship or resemblance in structure between species that suggests a common origin.
2. An attraction or force between particles that causes them to combine, as the attraction between an antigen and an antibody.

affinity
the condition of close relationship. Cf. consanguinity. See also marriage.
See also: Relationship
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.affinity - (immunology) the attraction between an antigen and an antibody
immunology - the branch of medical science that studies the body's immune system
attraction, attractive force - the force by which one object attracts another
2.affinity - (anthropology) kinship by marriage or adoption; not a blood relationship
anthropology - the social science that studies the origins and social relationships of human beings
family relationship, kinship, relationship - (anthropology) relatedness or connection by blood or marriage or adoption
steprelationship - a family relationship by virtue of remarriage
blood kinship, consanguinity, cognation - (anthropology) related by blood
3.affinity - (biology) state of relationship between organisms or groups of organisms resulting in resemblance in structure or structural parts; "in anatomical structure prehistoric man shows close affinity with modern humans"
biological science, biology - the science that studies living organisms
family relationship, kinship, relationship - (anthropology) relatedness or connection by blood or marriage or adoption
4.affinity - a close connection marked by community of interests or similarity in nature or character; "found a natural affinity with the immigrants"; "felt a deep kinship with the other students"; "anthropology's kinship with the humanities"
relation - an abstraction belonging to or characteristic of two entities or parts together
rapport, resonance - a relationship of mutual understanding or trust and agreement between people
sympathy - a relation of affinity or harmony between people; whatever affects one correspondingly affects the other; "the two of them were in close sympathy"
5.affinity - the force attracting atoms to each other and binding them together in a molecule; "basic dyes have an affinity for wool and silk"
force - (physics) the influence that produces a change in a physical quantity; "force equals mass times acceleration"
6.affinity - inherent resemblance between persons or things
resemblance - similarity in appearance or external or superficial details
7.affinity - a natural attraction or feeling of kinship; "an affinity for politics"; "the mysterious affinity between them"; "James's affinity with Sam"
attractiveness, attraction - the quality of arousing interest; being attractive or something that attracts; "her personality held a strange attraction for him"

affinity
Translations
affinity [əˈfɪnɪtɪ] nafinidad f
affinity [əˈfɪnɪtɪ] naffinité f
affinity [əˈfɪnɪtɪ] n to have an affinity with or for → sich verbunden fühlen mit;
(resemblance);
to have an affinity with → verwandt sein mit
affinity [əˈfɪnɪtɪ] naffinità f inv


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? Mentioned in ? References in periodicals archive
 
The improvement in homotypic neutralizing antibody titer and decrease in heterotypic neutralizing antibody titer described here is reminiscent of affinity maturation.
The Platform, called ProCode, can be configured for monoclonal antibody selection, affinity maturation and library generation, for improving solubility and bioactivity of biopharmaceuticals, as well as identification and characterization of protein-protein interactions and discovery of protein drugs.
XOMA's mAb platform includes leading commercial antibody display phage libraries, hybridoma, Human Engineering[TM], affinity maturation technologies, and a fully integrated product development infrastructure, including cell line and process development, preclinical and clinical functions, and manufacturing.
 
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