African trypanosomiasis


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African trypanosomiasis

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Human African trypanosomiasis (HAT), or sleeping sickness, is a tropical disease that affects sub-Saharan African countries.
DFMO is a drug used for African trypanosomiasis - an insect-borne parasitic disease of humans and other animals.
Human African trypanosomiasis (HAT), known as African sleeping sickness, is a protozoal infection, the West African form of which is caused by Trypanosoma brucei gambiense.
The following 18 NTDs have been designated by WHO for control or elimination: dengue and chikungunya, rabies, trachoma, buruli ulcer, yaws [endemic treponematoses], leprosy [Hansen's disease], Chagas disease, human African trypanosomiasis [sleeping sickness], leishmaniasis, taeniasis / cysticercosis, dracunculiasis [guinea-worm disease], echinococcosis, food-borne trematodiases, lymphatic filariasis, onchocerciasis [river blindness], schistosomiasis, soil-transmitted helminthiases, and mycetoma.
Cases of human African trypanosomiasis (sleeping sickness) have been reduced from 37,000 new cases in 1999 to well under 3,000 cases in 2015.
The disease is officially known as Human African trypanosomiasis, but takes its more common name from the coma that results when the parasite penetrates the brain.
Anemia is considered as a major and important indicator of trypanosomiasis infection in camel and in human African trypanosomiasis.
It also reviews key players involved in the therapeutic development for African Trypanosomiasis and special features on late-stage and discontinued projects.
Induction of the trypanosome lymphocyte-triggering factor (TLTF) and neutralizing antibodies to the TLTF in experimental african trypanosomiasis.
In fact, the WHO acknowledges that there are only three diseases that are genuinely 'neglected': African trypanosomiasis, leishmaniosis and Chagas disease.
Rocky Mountain Spotted Fever, other rickettsiae, Lyme Disease, mycoplasma, typhoid fever, ehrlichiosis, plague Protozoa: Toxoplasmosis, malaria, African trypanosomiasis, American trypanosomiasis Helminths: Larval migrans, schistosomiasis Noninfectious conditions Reactions: Drug reaction, foreign body reaction Rheumatologic: vasculitis (erythromelalgia, erythema nodosum, other).
Human African trypanosomiasis is on the World Health Organization's (WHO) list of neglected tropical diseases and since 2013 has become a target for eradication.

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