macroglobulin

(redirected from Alpha-2 macroglobulin)
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mac·ro·glob·u·lin

 (măk′rō-glŏb′yə-lĭn)
n.
A plasma globulin of high molecular weight.

macroglobulin

(ˌmækrəʊˈɡlɒbjʊlɪn)
n
1. (Biochemistry) an immunoglobulin of unusually high relative molecular mass, observed in the blood in some diseases
2. (Biochemistry) Also called: immunoglobulin M the normal form of this immunoglobulin
References in periodicals archive ?
Efficacy data from subjects with longer clots or smaller drops in alpha-2 macroglobulin, which rapidly and irreversibly inactivates alfimeprase, suggest improved retention of alfimeprase at the site of the clot might improve lysis.
In addition, preliminary testing suggests that its lytic activity is localized to the site of delivery because within seconds of moving away from the clot and into the general circulation it is inhibited by alpha-2 macroglobulin, a naturally occurring protein in our blood.
Alfimeprase is inhibited within seconds of moving away from the clot and into the general circulation by alpha-2 macroglobulin, a naturally occurring protein in our blood.
Alpha-2 macroglobulin is genetically associated with Alzheimer disease.
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