macroglobulin

(redirected from Alpha-2 macroglobulin)
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mac·ro·glob·u·lin

 (măk′rō-glŏb′yə-lĭn)
n.
A plasma globulin of high molecular weight.

macroglobulin

(ˌmækrəʊˈɡlɒbjʊlɪn)
n
1. (Biochemistry) an immunoglobulin of unusually high relative molecular mass, observed in the blood in some diseases
2. (Biochemistry) Also called: immunoglobulin M the normal form of this immunoglobulin
References in periodicals archive ?
Increased concentrations of alpha-2 macroglobulin inhibit mesangial proteases, thus retarding the removal of basement membrane.
In addition, preliminary testing suggests that its lytic activity is localized to the site of delivery because within seconds of moving away from the clot and into the general circulation it is inhibited by alpha-2 macroglobulin, a naturally occurring protein in our blood.
Alfimeprase is inhibited within seconds of moving away from the clot and into the general circulation by alpha-2 macroglobulin, a naturally occurring protein in our blood.
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