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alpha helix
(redirected from Alpha-helix)

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
alpha helix
n.
A common structure of proteins, characterized by a single, spiral chain of amino acids stabilized by hydrogen bonds.

alpha-heli·cal (lf-hl-kl, -hl-) adj.

alpha helix
n
(Life Sciences & Allied Applications / Biochemistry) Biochem a helical conformation of a polypeptide chain, found abundantly in the structure of proteins

alpha helix
A common structure of proteins, characterized by a single, spiral chain of amino acids stabilized by hydrogen bonds. Compare beta sheetrandom coil


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Proline +side chain of proline & alpha-amino group form a ring structure +it contains an imino group +unique geometry of proline (help forming of fibrous structure of collagen) +that interrupts alpha-helix found in globular proteins.
Whereas a single alpha-helix consists of an elegant spiral of 15 to 20 amino acids, the beta sheet requires 60 to 70 amino acids.
ALPHA-HELIX MIMETICS IN DRUG DISCOVERY 281 Hang Yin, Gui-In Lee, and Andrew D.
 
 
 
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