melanocyte-stimulating hormone

(redirected from Alpha-melanocyte-stimulating hormone)
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mel·a·no·cyte-stim·u·lat·ing hormone

 (mĕl′ə-nō-sīt′stĭm′yə-lā′tĭng, mə-lăn′ə-)
n. Abbr. MSH
A hormone secreted by the pituitary gland that regulates skin color in humans and other vertebrates by stimulating melanin synthesis in melanocytes and melanin granule dispersal in melanophores. Also called intermedin.


melanocyte-stimulating hormone: a pituitary gland hormone that causes darkening of the skin by increasing the production of melanin.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.melanocyte-stimulating hormone - a hormone secreted by the anterior pituitary gland that controls the degree of pigmentation in melanocytes
endocrine, hormone, internal secretion - the secretion of an endocrine gland that is transmitted by the blood to the tissue on which it has a specific effect
References in periodicals archive ?
The mechanism of action is thought to be analogous to a peptide alpha-melanocyte-stimulating hormone that is thought to enhance dopamine and norepinephrine, said Dr.
Leptin is mainly produced by adipocytes and acts via the particular receptor OB-Rb, decreases food intake by motivation the anorexigenic peptide alpha-melanocyte-stimulating hormone peptide ([alpha]-MSH).
Afamelanotide, a first-in-class investigational chemical analogue of alpha-melanocyte-stimulating hormone, is a melanocortin-1 agonist that activates melanocytes and increases melanin levels in the skin.