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Bremelanotide, which is a melanocortin 4 receptor agonist drug candidate, is a synthetic peptide analog of the naturally occurring hormone alpha-MSH (melanocyte-stimulating hormone).
Alpha-MSH when released from the anterior pituitary, is a potent natural antipyretic agent that antagonizes the fever induced by IL-1, IL-6 and TNF-alpha.
Bremelanotide, like alpha-MSH, is thought to modulate brain pathways involved in sexual response, Dr.
Nillni, professor of medicine at Brown University and a researcher at Rhode Island Hospital, observed that after meals obese rats had a dearth of another key hormone -- alpha-MSH -- compared to rats of normal weight.
It is a synthetic peptide analog of the naturally existing hormone alpha-MSH (melanocyte-stimulating hormone).
Melitane is a biomimetic peptide derived from alpha-MSH.

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