melanocyte-stimulating hormone

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mel·a·no·cyte-stim·u·lat·ing hormone

 (mĕl′ə-nō-sīt′stĭm′yə-lā′tĭng, mə-lăn′ə-)
n. Abbr. MSH
A hormone secreted by the pituitary gland that regulates skin color in humans and other vertebrates by stimulating melanin synthesis in melanocytes and melanin granule dispersal in melanophores. Also called intermedin.


melanocyte-stimulating hormone: a pituitary gland hormone that causes darkening of the skin by increasing the production of melanin.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.melanocyte-stimulating hormone - a hormone secreted by the anterior pituitary gland that controls the degree of pigmentation in melanocytes
endocrine, hormone, internal secretion - the secretion of an endocrine gland that is transmitted by the blood to the tissue on which it has a specific effect
References in periodicals archive ?
Bremelanotide, which is a melanocortin agonist (a compound which binds to a cell receptor and triggers a response) drug candidate, is a synthetic peptide analog of the naturally occurring hormone alpha-MSH (melanocyte-stimulating hormone).
Bremelanotide, like alpha-MSH, is thought to modulate brain pathways involved in sexual response, Dr.
Nillni, professor of medicine at Brown University and a researcher at Rhode Island Hospital, observed that after meals obese rats had a dearth of another key hormone -- alpha-MSH -- compared to rats of normal weight.
It is a synthetic peptide analog of the naturally existing hormone alpha-MSH (melanocyte-stimulating hormone).
Melitane is a biomimetic peptide derived from alpha-MSH.
Previous studies show that the substance, called alpha melanocyte stimulating hormone, or alpha-MSH, has anti-inflammatory properties.
Melatonin, prolactin and alpha-MSH, hormones known to control sharks' skin coloration, are key in regulating glow.
It is now established that leptin action in the hypothalamus in regulation of food intake and body weight is mediated by a neural circuitry comprising of orexigenic and anorectic signals, including NPY, MCH, galanin, orexin, GALP, alpha-MSH, NT, and CRH.
The patented technologies invented by a team of researchers at CTT's client, the University of Arizona, are synthetic analogues of alpha-MSH (alpha-melanocyte-stimulating hormone), a natural hormone secreted by the pituitary gland and skin cells.

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