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melanocyte-stimulating hormone
(redirected from Alpha-msh)

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
mel·a·no·cyte-stim·u·lat·ing hormone  (ml-n-ststmy-ltng, m-ln-)
n. Abbr. MSH
A hormone secreted by the pituitary gland that regulates skin color in humans and other vertebrates by stimulating melanin synthesis in melanocytes and melanin granule dispersal in melanophores. Also called intermedin.

melanocyte-stimulating hormone
A hormone that is secreted by the pituitary gland and regulates skin color by stimulating melanin synthesis in humans and other vertebrates. Melanocyte-stimulating hormone stimulates the melanin-producing cells (called melanocytes) of mammals and the melanin-containing cells (called melanophores) of reptiles and amphibians.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.melanocyte-stimulating hormone - a hormone secreted by the anterior pituitary gland that controls the degree of pigmentation in melanocytes
endocrine, hormone, internal secretion - the secretion of an endocrine gland that is transmitted by the blood to the tissue on which it has a specific effect


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Researchers found that blocking the PRCP enzyme keeps the alpha-MSH peptides from being degraded, resulting in higher levels of alpha-MSH and decreased appetite.
It is now established that leptin action in the hypothalamus in regulation of food intake and body weight is mediated by a neural circuitry comprising of orexigenic and anorectic signals, including NPY, MCH, galanin, orexin, GALP, alpha-MSH, NT, and CRH.
It works with the hormone alpha-MSH to darken the skin and reduce appetite.
 
 
 
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