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 (ăl′fə-fē′tō-prō′tēn, -tē-ĭn)
n. Abbr. AFP
A glycoprotein that is abundant in the blood plasma of human and other mammalian fetuses and is also present in the serum of people with certain diseases, such as liver cancer. Abnormal levels in maternal serum are associated with certain fetal abnormalities, including Down syndrome and spina bifida.


(Biochemistry) a protein that forms in the liver of the human fetus. Excessive quantities in the amniotic fluid and maternal blood may indicate spina bifida in the fetus; low levels may point to Down's syndrome. Abbreviation: afp


(ˌfi toʊˈproʊ tin, -ti ɪn)

a serum protein produced during pregnancy, useful in the prenatal diagnosis of multiple births or birth defects. Abbr.: AFP
References in periodicals archive ?
Alphafetoprotein in the Dutch External Quality Assurance programme: a need for improvement.
The EMA study population was drawn from live-born children in three counties from Southern California (Orange, San Diego, and Imperial) in 2000-2003 whose mothers were enrolled in the state's Expanded Alphafetoprotein Prenatal Screening Program.
The possibility of this diagnosis should be entertained especially if the serum alphafetoprotein levels are not elevated.
11,12 Elevated serum alphafetoprotein has also been associated with abdominal pregnancy.
Sung, "Serum alphafetoprotein in hepatocellular carcinoma," Cancer, vol.
Aflatoxin Exposure Produces Se-rum Alphafetoprotein Elevations and Marked Oval Cell Proliferation in Young Male Pekin Ducklings.
Laboratory tests, including serum alphafetoprotein (aFP) and beta-human chorionic gonadotropin (HCG) levels, were within normal limits.
5) Alphafetoprotein (AFP) has been shown to be reliable indicator of disease activity and some authors advocate investigating teratoma recurrence by doing serial serum AFP levels.
Evaluating fetomaternal hemorrhage by alphafetoprotein and Kleihauer following therapeutic abortions.
All patients in the liver cohort underwent abdominal ultrasound, standard liver function tests (LFTs), detailed screening of secondary causes of liver disease, HA level, platelet count, and alphafetoprotein measurements.