Activase

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Noun1.Activase - a thrombolytic agent (trade name Activase) that causes fibrinolysis at the site of a blood clotActivase - a thrombolytic agent (trade name Activase) that causes fibrinolysis at the site of a blood clot; used in treating acute myocardial infarction
clot buster, thrombolytic, thrombolytic agent - a kind of pharmaceutical that can break up clots blocking the flow of blood to the heart muscle
brand, brand name, marque, trade name - a name given to a product or service
References in periodicals archive ?
Most studies of alteplase use in the treatment of DVT have involved systemic administration.
Food and Drug Administration (FDA) a Supplemental Biologic License Application (sBLA) for Alteplase, recombinant (Activase) for use in restoring function to catheters that have become blocked, preventing the withdrawal of blood samples or infusion of vital fluids to medically ill patients.
Given the high rate of pipeline attrition in this market, investigators also remain focused on improving the utility of recombinant tissue plasminogen activator (rt-PA; alteplase [Genentech's Activase, Boehringer Ingelheim's Actilyse, Kyowa Hakko Kirin's Activacin, Mitsubishi Tanabe Pharma's Grtpa]), the current standard of care in acute ischemic stroke, through new research, including the use of advanced imaging to expand the treatment window beyond the currently-accepted 4.
Pharmacokinetics of alteplase in the treatment of ischaemic stroke.
Patients who have suffered from an ischaemic stroke, a type of stroke caused by a blockage in the arteries that supply blood to the brain, can safely be given the drug alteplase within four and a half hours after the onset of symptoms, the National Institute for Clinical Excellence (Nice) said.
Patients across the town suffering an attack will now be able to get clot-busting drug Alteplase along with thrombolysis treatment at their local hospital day and night.
Although current best evidence suggests that submassive PE should receive anticoagulation and thrombolysis (1), alteplase was withheld due to a significant history of active dyspepsia and upper GI ulceration.
In the second study, more than half (51%) of 216 patients treated with alteplase in London, Ont.
In the Ontario study--a prospective study of acute stroke patients who received alteplase at a university hospital over a 4-year period--investigators reported that a lack of improvement at 24 hours was associated with poor patient outcomes and death at 3 months.
Dr Martin James, Consultant Stroke Physician at The Royal Devon and Exeter NHS Foundation Trust, and British Association of Stroke Physicians Former President, says "Extending the licensed time window for thrombolysis treatment with alteplase to 4.
Drugs and Drugs, Vitamin supplements, scopolamine hydrobromide, Alteplase