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Ames test

   Also found in: Medical, Legal, Financial, Encyclopedia, Wikipedia, Hutchinson 0.04 sec.
Ames test
n.
A test used to determine the mutagenic potential of a substance based on the mutation rate of bacteria that are exposed to the substance.

[After Bruce Ames (born 1928), American biochemist.]

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, inventor of the Ames test for mutagenicity and professor of biochemistry and molecular biology at U.
APM was not genotoxic in the following tests: dominant lethal mutation assay in rats, host-mediated assay in rats and mice, in vivo cytogenetic assay in rats, and the Ames test (Kotsonis and Hjelle 1996).
Commonly found in feces, 7-OHIQ was identified during the 1980s as a direct-acting mutagen in the Ames test, a bacterial assay used to screen for potential carciongens.
 
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