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aminoglycoside
(redirected from Aminoglycosides)

   Also found in: Medical, Wikipedia 0.01 sec.
a·mi·no·gly·co·side  (-mn-glk-sd, m-)
n.
Any of a group of broad-spectrum antibiotics, such as streptomycin, derived from species of Streptomyces or Micromonospora bacteria and used to treat infections caused by gram-negative bacteria.

aminoglycoside  (-mn-glk-sd, m-)
1. A compound containing amino sugars in glycoside linkage.
2. Any of a group of antibiotics, such as streptomycin, having the chemical structure of this compound, derived from species of Streptomyces or Micomonospora bacteria and usually used to treat infections caused by gram-negative bacteria.


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Aminoglycosides generate free radicals within the inner ear by activating inducible nitric oxide synthetase and therefore increasing nitric oxide concentrations.
The ototoxicity receives a boost due to the fact that they are prescribed together with aminoglycosides in most cases.
Either way, there has not been enough monitoring or investigation of apramycin usage for satisfactory answers to the questions raised by this research, which suggests that restricted use of apramycin, even for therapeutic purposes cannot guarantee that resistance to aminoglycosides important in the human medicine will not be selected.
 
 
 
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