gene therapy

(redirected from Antibody genes)
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gene therapy

n.
The treatment of certain medical disorders, especially those caused by genetic anomalies or deficiencies, by introducing specific engineered genes into a patient's cells.

gene therapy

n
(Genetics) the replacement or alteration of defective genes in order to prevent the occurrence of such inherited diseases as haemophilia. Effected by genetic engineering techniques, it is still at the experimental stage

gene′ ther`apy


n.
the treatment of a disease by replacing aberrant genes with normal ones, esp. through the use of viruses to transport the desired genes into the nuclei of blood cells.
[1970–75]

gene therapy

The treatment of disease, especially one caused by the inheritance of a defective gene, by replacing defective genes with healthy ones through genetic engineering.
Translations
thérapie génique
génterápia

gene therapy

n (Med) → Gentherapie f
References in periodicals archive ?
They added their huge library of antibody genes to the population of cells: each cell ended up containing the genes for one or more of the antibodies.
In addition to the antibody genes and those encoding the Cas9 enzyme and guide RNA, the researchers inserted a gene that would cause mosquitoes' eyes to glow red under fluorescent lights, enabling the team to easily find insects of interest.
These antibodies are part of animal immune systems while plantibody is an antibody produced by genetically modified crops and are produced in plants by transforming them with antibody genes from animals.
AID is best known as a master regulator of antibody diversity in B cells, and in order to create varied types of beneficial antibodies, it routinely mutates antibody genes.
They had low levels of inflammatory gene expression and strong expression of antiviral and antibody genes.
They have discovered that a good number of our antibody genes, how well they operate and, potentially, what they fight off, actually vary from person to person.
Research suggested that GANP is important in the reconstruction of antibody genes.
This would require either a huge amount of genome devoted to antibody genes, or a diversity generation mechanism.
The resulting antigenized antibody genes were cloned into mammalian expression vector.
In 2002 Kirin made use of a proprietary human artificial chromosome vector to introduce human antibody genes into bovine cells and, using Hematech's technology, created cows capable of producing human antibody proteins and bovine antibody proteins.
The company said CAT's antibody libraries contain the information for over 100 billion different antibody genes.
For the process to be practical, however, Echelard said that it is "very likely" that the cows' own antibody genes will have to be deactivated, "so their expression does not interfere with the expression of the human genes.