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Related to Antigenic drift: Original antigenic sin


 (ăn′tĭ-jən) also an·ti·gene (-jēn′)
A molecule that is capable of binding to an antibody or to an antigen receptor on a T cell, especially one that induces an immune response. An antigen is usually a foreign substance, such as a toxin or a component of a virus, bacterium, or parasite.

an′ti·gen′ic (-jĕn′ĭk) adj.
an′ti·gen′i·cal·ly adv.
an′ti·ge·nic′i·ty (-jə-nĭs′ĭ-tē) n.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Adj.1.antigenic - of or relating to antigens


a. antigénico-a, que tiene las propiedades de un antígeno;
___ determinantdeterminante ___;
___ driftvariaciones antigénicas menores;
___ shiftvariación ___ mayor;
___ specificityespecificidad ___.
References in periodicals archive ?
To date, a predominant subclade of A(H3N2) viruses with substantial antigenic drift has yet to emerge, and extensive genetic variation exists in the circulating virus population.
Both are antigenically similar with no antigenic drift," a spokesman for the CHP said.
70) Recently, the documentation of the antigenic drift from the vaccine strain in a majority of considered isolates raised concern that vaccine effectiveness might be suboptimal, especially in older ages or specific high-risk groups.
The two new mechanisms of change in influenza strains are antigenic drift and antigenic shift.
Influenza vaccines are less effective when antigenic drift occurs (i.
This may be due to less degree of antigenic drift in the influenza virus.
In the 2014-2015 influenza season, an antigenic drift in the circulating H3N2 virus rendered influenza vaccines only 23% effective in preventing laboratory-confirmed influenza.
67 millions for the project title "Combating Avian Influenza Through systematic Analysis of Antigenic Drift Genetic Variations development Of Novel Diagnostic Tool and Vaccines".
Accumulation of genetic mutations termed antigenic drift, allows influenza viruses to inflict yearly epidemics that may result in 250,000 to 500,000 deaths annually.
Finally, significant antigenic diversity of noroviruses and the constant antigenic drift may.
These seasonal epidemics are the result of antigenic drift, a phenomenon caused by mutations in two key viral genes due to an error-prone RNA polymerase.
This evasion strategy, called antigenic drift, is why a new flu vaccine is necessary every year, a process that can take upwards of seven months.