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Related to Antigenic drift: Original antigenic sin


 (ăn′tĭ-jən) also an·ti·gene (-jēn′)
A molecule that is capable of binding to an antibody or to an antigen receptor on a T cell, especially one that induces an immune response. An antigen is usually a foreign substance, such as a toxin or a component of a virus, bacterium, or parasite.

an′ti·gen′ic (-jĕn′ĭk) adj.
an′ti·gen′i·cal·ly adv.
an′ti·ge·nic′i·ty (-jə-nĭs′ĭ-tē) n.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Adj.1.antigenic - of or relating to antigens


a. antigénico-a, que tiene las propiedades de un antígeno;
___ determinantdeterminante ___;
___ driftvariaciones antigénicas menores;
___ shiftvariación ___ mayor;
___ specificityespecificidad ___.
References in periodicals archive ?
Further, the report states that one of the main challenges in the market is the antigenic drift in influenza vaccines.
Antigenic drift of the pandemic 2009 A(H1N1) influenza virus in A ferret model.
Accumulation of genetic mutations termed antigenic drift, allows influenza viruses to inflict yearly epidemics that may result in 250,000 to 500,000 deaths annually.
These seasonal epidemics are the result of antigenic drift, a phenomenon caused by mutations in two key viral genes due to an error-prone RNA polymerase.
This evasion strategy, called antigenic drift, is why a new flu vaccine is necessary every year, a process that can take upwards of seven months.
Current influenza vaccines may be safe and immunogenic, but they are highly vulnerable to antigenic drift and shift, which compromise efficacy and require reformulation and repeated immunization.
During the 2009/2010 Northern Hemisphere influenza season, little antigenic drift occurred in circulating H1N1 (7) and the clinical manifestations remain generally mild.
These viruses are able to mutate and change very rapidly in a host due to their ability to undergo antigenic drift and/or antigenic shift.
The findings in mice, using a strain of seasonal influenza virus first isolated in 1934, also suggest that antigenic drift might be slowed by increasing the number of children vaccinated against influenza.
This strategy, known as antigenic drift, works well as a short-term survival tactic for the virus: the speed with which slight variations develop keeps populations susceptible to infection.
Frequent antigenic change, known as antigenic drift, is caused by mutations during reproduction of the virus, and results in new variants of influenza.
No significant antigenic drift of novel H1N1 virus away from what is in the vaccine has been encountered so far in the United States, he said.