antimetabolite(redirected from Antimetabolites)
Also found in: Thesaurus, Medical, Encyclopedia.
Related to Antimetabolites: topoisomerase inhibitors, plant alkaloids
A substance that closely resembles an essential metabolite and therefore inhibits physiological reactions involving that metabolite.
an′ti·met′a·bol′ic (-mĕt′ə-bŏl′ĭk) adj.
(Pharmacology) any drug that acts by disrupting the normal growth of a cell. Sulfonamide drugs are antimetabolites and some antimetabolites are used in cancer treatment
an•ti•me•tab•o•lite(ˌæn ti məˈtæb əˌlaɪt, ˌæn taɪ-)
any substance that interferes with growth by competing with a nutrient metabolite for receptors or enzymes in the body, used esp. for treating certain cancers.
an`ti•met`a•bol′ic (-ˌmɛt əˈbɒl ɪk) adj.
Switch to new thesaurus
|Noun||1.||antimetabolite - an antineoplastic drug that inhibits the utilization of a metabolite|
antineoplastic, antineoplastic drug, cancer drug - any of several drugs that control or kill neoplastic cells; used in chemotherapy to kill cancer cells; all have unpleasant side effects that may include nausea and vomiting and hair loss and suppression of bone marrow function
fluorouracil - an antimetabolite used to treat certain cancers
mercaptopurine, Purinethol - a drug (trade name Purinethol) that interferes with the metabolism of purine and is used to treat acute lymphocytic leukemia