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antimetabolite
(redirected from Antimetabolites, antineoplastic)

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
an·ti·me·tab·o·lite  (nt-m-tb-lt, nt-)
n.
A substance that closely resembles an essential metabolite and therefore interferes with physiological reactions involving it.

anti·meta·bolic (-mt-blk) adj.

antimetabolite [ˌæntɪmɪˈtæbəˌlaɪt]
n
(Medicine / Pharmacology) any drug that acts by disrupting the normal growth of a cell. Sulfonamide drugs are antimetabolites and some antimetabolites are used in cancer treatment
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.antimetabolite - an antineoplastic drug that inhibits the utilization of a metabolite
antineoplastic, antineoplastic drug, cancer drug - any of several drugs that control or kill neoplastic cells; used in chemotherapy to kill cancer cells; all have unpleasant side effects that may include nausea and vomiting and hair loss and suppression of bone marrow function
fluorouracil - an antimetabolite used to treat certain cancers
mercaptopurine, Purinethol - a drug (trade name Purinethol) that interferes with the metabolism of purine and is used to treat acute lymphocytic leukemia
amethopterin, methotrexate, methotrexate sodium - toxic antimetabolite that limits cellular reproduction by acting as an antagonist to folic acid; used to treat certain cancers and psoriasis and rheumatoid arthritis


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