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apoptosis
(redirected from Apoptotic)

   Also found in: Medical, Encyclopedia, Wikipedia, Hutchinson 0.03 sec.
ap·op·to·sis  (pp-tss, p-t-)
n.
Disintegration of cells into membrane-bound particles that are then eliminated by phagocytosis or by shedding.

apoptosis [ˌæpəpˈtəʊsɪs]
n
(Life Sciences & Allied Applications / Biology) Biology the programmed death of some of an organism's cells as part of its natural growth and development Also called programmed cell death
[from Greek: a falling away, from apo- + ptōsis a falling]

apoptosis  (pp-tss, p-t-)
A natural process of self-destruction in certain cells, such as epithelial cells and erythrocytes, that are genetically programmed to have a limited life span or are damaged. Apoptosis can be induced either by a stimulus, such as irradiation or toxic drugs, or by removal of a repressor agent. The cells disintegrate into membrane-bound particles that are then eliminated by phagocytosis. Also called programmed cell death.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.apoptosis - a type of cell death in which the cell uses specialized cellular machinery to kill itself; a cell suicide mechanism that enables metazoans to control cell number and eliminate cells that threaten the animal's survival
cell death, necrobiosis - (physiology) the normal degeneration and death of living cells (as in various epithelial cells)


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By impairing the development of adaptive immune responses needed for recovery, the apoptotic destruction of lymphocytes and dendritic cells could have a particularly adverse effect on disease outcome.
In addition, we used reverse-transcriptase polymerase chain reaction and Western blotting to demonstrate significantly increased levels of the apoptotic effecter caspase-3 in treated animal hearts.
In animal models, histologic findings resemble apoptotic cell death rather than necrosis.
 
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