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apoptosis
(redirected from Apoptotic cell death)

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
ap·op·to·sis  (pp-tss, p-t-)
n.
Disintegration of cells into membrane-bound particles that are then eliminated by phagocytosis or by shedding.

apoptosis [ˌæpəpˈtəʊsɪs]
n
(Life Sciences & Allied Applications / Biology) Biology the programmed death of some of an organism's cells as part of its natural growth and development Also called programmed cell death
[from Greek: a falling away, from apo- + ptōsis a falling]

apoptosis  (pp-tss, p-t-)
A natural process of self-destruction in certain cells, such as epithelial cells and erythrocytes, that are genetically programmed to have a limited life span or are damaged. Apoptosis can be induced either by a stimulus, such as irradiation or toxic drugs, or by removal of a repressor agent. The cells disintegrate into membrane-bound particles that are then eliminated by phagocytosis. Also called programmed cell death.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.apoptosis - a type of cell death in which the cell uses specialized cellular machinery to kill itself; a cell suicide mechanism that enables metazoans to control cell number and eliminate cells that threaten the animal's survival
cell death, necrobiosis - (physiology) the normal degeneration and death of living cells (as in various epithelial cells)


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Oxygen radicals then react with the nitric oxide to form the destructive peroxynitrite radical, which can directly stimulate mitochondrial-mediated apoptotic cell death.
p53 is activated in response to a variety of stress signals, dictating a variety of biochemical and biological outcomes, ranging from effective repair of minor damage to arresting cell cycle progression and induction of apoptotic cell death.
 
 
 
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