atovaquone


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a·to·va·quone

 (ə-tō′və-kwōn′)
n.
A drug, C22H19ClO3, used to treat pneumonia caused by pneumocystis fungi and, in combination with proguanil, to prevent or treat malaria.

[Perhaps rearrangement of the letters of Aōt(us), night monkey genus on which testing was carried out during the development of atovaquone (Greek a-, without; see a-1 + ous, ōt-,, ear (from the small external ears of night monkeys); see otic) + (par)vaquone, veterinary drug chemically related to atovaquone (parva, specific epithet of Theileria parva, apicomplexan cattle pathogen against which parvaquone is effective, from Latin parva, feminine of parvus, small (from the relatively small size of the pathogen); see pau- in Indo-European roots) + qu(in)one.]
Translations

atovaquone

n atovacuona
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References in periodicals archive ?
While quinine was isolated from the bark of the cinchona tree in 1820, chloroquine, proguanil, mefloquine, and atovaquone each were developed during or after a military conflict during 1945-1985.
In addition, the sustained release of other antimalarial drugs, atovaquone and doxycycline, were demonstrated in vivo with their respective ProNeura-based implants.
The most common initial clinical signs and symptoms of babesiosis (fever, fatigue, chills, and diaphoresis) are nonspecific and present diagnostic challenges that can contribute to delays in diagnosis and effective treatment with atovaquone and azithromycin (1).
After laboratory confirmation of malaria diagnosis, the therapy was changed to a 3-day course of atovaquone and proguanil.
cytophilum) Babesiosis 1 week-2 months Atovaquone 750 mg po bid + (Babesia azithromycin 500-1,000 mg po day 1 microti) decrease to 250-1,000 mg po bid after initial dose x 7-10 days.
Efficacy of atovaquone combined with clindamycin against murine infection with a cystogenic (Me49) strain of Toxoplasma gondii.
In 2000, Krause, who had published concerns of suboptimal results with clindamycin and quinine therapy, reported low side effect and high success with a short course of atovaquone (Mepron) liquid at a dose of 1500 mg/day used in the presence of azithromycin (Zithromax) 500 mg/day.
Primary treatment is Atovaquone and Zithromax given for seven days.
She was continued on her hydroxychloroquine and placed on various supplementary agents, such as atovaquone for pneumocystis jiroveci prophylaxis, calcium and vitamin D as indicated, and deep venous thrombosis as well as gastrointestinal prophylaxis as indicated.
Carola Hunte has succeeded in describing how the antimalarial drug atovaquone binds to its target protein.
M2 EQUITYBITES-June 2, 2014-Mylan launches Atovaquone and Proguanil Hydrochloride Tablets