Regulators in the United States have approved a drug for women with advanced breast cancer caused by BRCA gene
mutations, which disproportionately affects Ashkenazi Jewish women.
Known as rucaparib, the drug offers a lifeline to women with advanced ovarian cancer, who have received two or more prior chemotherapies and whose tumours have a BRCA gene
Officially known as rucaparib, the drug offers a lifeline to women with advanced ovarian cancer, who have received two or more prior chemotherapies and whose tumours have a BRCA gene
In trials, women with an inherited defect in the BRCA gene
found their relapse time was extended from five-anda-half months to 21 months.
A study unveiled at the 36th Annual National Society of Genetic Counselors suggests transgender individuals should be aware of their family history of breast cancer and consider getting tested for the BRCA gene
mutations before they make decisions about medical interventions.
Caption: BRCA gene
mutations have previously been associated with aggressive treatment.
Dundee mum Aimi, who had her breasts removed after learning she had the rogue BRCA gene
, said: "The giggling and laughing stops quickly when people realise how serious the message is.
Food and Drug Administration today expanded the approved use of Lynparza (olaparib tablets) to include the treatment of patients with certain types of breast cancer that have spread (metastasized) and whose tumors have a specific inherited (germline) genetic mutation, making it the first drug in its class (PARP inhibitor) approved to treat breast cancer, and it is the first time any drug has been approved to treat certain patients with metastatic breast cancer who have a BRCA gene
Young women with the BRCA gene
mutation that prompted actress Angelina Jolie's pre-emptive and much-publicised double mastectomy are not more likely to die after a breast cancer diagnosis, scientists said Friday.
Much current research into breast cancer diagnostics and therapeutics has focused on three types of the disease: triple-negative cancer, cancer that is linked to HER2 gene amplification, and cancer that is linked to BRCA gene
It wasn't until my cousin Marilyn phoned to say she had been diagnosed with breast cancer and the BRCA gene
and that her genetic counsellor had suggested that all the family should be tested, that I took notice.
This new class of medications is most effective in ovarian cancer patients who have a mutation in the BRCA gene
, and is administered orally.