Raxibacumab is a fully human monoclonal antibody, which received approval from the US Food and Drug Administration for the treatment and prophylaxis of inhalational anthrax due to Bacillus anthracis
In the United States, Bacillus anthracis
is a select agent and is subject to select agent requirements under the U.
Anthrax is a disease of herbivorous animals caused by Bacillus anthracis
and humans incidentally acquire the disease by handling infected dead animals and their products.
Phylogenetic analysis revealed that sequenced strain showed a close phylogenecity with Bacillus anthracis
strain 1144 and Bacillus anthracis
Exposure to Bacillus anthracis
bacteria, particularly if inhaled, can lead to death if not immediately treated.
Inhalational anthrax is caused by breathing in Bacillus anthracis
spores, which can occur after exposure to infected animals or contaminated animal products, or as a result of an intentional release of spores.
The organism that causes anthrax infection, Bacillus anthracis
Anthrax is an acute disease caused by the bacterium Bacillus anthracis
A large, gram-positive, rod (bacillus), Bacillus anthracis
is the causative agent of anthrax (Greek for "coal"), named for the black lesions of cutaneous anthrax.
Anthrax disease is caused by the bacterium Bacillus anthracis
, which produces two deadly toxins: lethal toxin and edema toxin.
The topics include the scientific and ethical importance of animal models in biodefense research, characterizing new and advancing existing animal models of Bacillus anthracis
infection, alphaviruses, animal models for viral hemorrhagic fevers, and in vitro and in vivo assays for staphylococcal and streptococcal superantigens.
The designation of the case as anthraxlike led me to compare it with the 41 documented cases in the 1979 Sverdlovsk (now Yekaterinburg), Russia, outbreak of inhalational anthrax associated with accidental release of Bacillus anthracis
spores from a biologic weapons facility.