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lactam
(redirected from Beta-lactam Ring)

   Also found in: Medical, Encyclopedia, Wikipedia 0.03 sec.
lactam [ˈlæktæm]
n
(Chemistry / Elements & Compounds) Chem any of a group of inner amides, derived from amino acids, having the characteristic group -CONH-
[from lact(one) + am(ide)]


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? Mentioned in ? References in periodicals archive
 
have a beta-lactam ring that is essential to their activity, the inhibition of bacterial cell wall synthesis.
The major metabolite of ertapenem is the inactive ring-opened derivative formed by hydrolysis of the beta-lactam ring.
MethylGene has designed, synthesized and developed a family of small molecule inhibitors that do not contain a beta-lactam ring and yet, are able to mimic the inhibitory activity of beta-lactam-based beta-lactamase inhibitors.
 
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