beta-lactam

(redirected from Beta-lactams)
Also found in: Medical.
Related to Beta-lactams: Tetracyclines, Macrolides, Fluoroquinolones

be·ta-lac·tam

 (bā′tə-lăk′təm, bē′-)
n.
1. A lactam composed of a four-membered ring, formed by intramolecular condensation of an amino acid in which the amino group is located at the beta position, or any compound containing this group.
2. A beta-lactam antibiotic.

[beta, second (in the series of lactam rings, the first being the simplest) + lactam.]
References in periodicals archive ?
The report includes the results of in vitro and preclinical in vivo studies, which demonstrate the ability of ETX2514 to restore antimicrobial activity in combination with multiple beta-lactams against Gram-negative, multi-drug resistant pathogens.
Ramsey: The switch from second-line options to beta-lactams saved an estimated $780 per patient and close to $40,000 overall.
MRSA and related resistant bacteria can withstand a group of antibiotics called beta-lactams, which includes penicillin and methicillin.
com)-- Bioo Scientific's MaxSignal[R] Beta-Lactam ELISA Test Kit has been validated for the screening of a wide range of beta-lactam antibiotics including ampicillin, penicillin G, amoxicillin, azlocillin, piperacillin, nafcillin, cloxacillin, oxacillin, cefoperazone, ceftiofur and other beta-lactams in a number of food matrices.
Clindamycin and beta-lactams were equally effective as first-line empiric therapy (Pediatrics 2009; 123:e959-66).
The interdisciplinary team, which included Mitzi Nagarkatti and Alan Decho, from the university's School of Medicine and Arnold School of Public Health, respectively, also showed that the antimicrobial effectiveness of the four beta-lactams studied in detail was enhanced by the polymer.
SAN FRANCISCO -- Treatment of Shiga toxin-producing Escherichia coli 0157 infection with beta-lactams is associated with increased risk for post-diarrheal hemolytic uremic syndrome in both children and adults, according to findings from a population-based study.
One 2 One[R] has developed fill and finish expertise in a wide range of products, such as: Biologics, Small Molecules, Vaccines, Highly Potent Drugs, Beta-Lactams, and Cytotoxics.
Amino glycosides and beta-lactams may be more effective when combined with another agent for initial therapy of these upper-tract infection patients.
aeruginosa may be treated with antimicrobial agents from three major groups based on mechanism of action: aminoglycosides (interference with protein synthesis) such as tobramycin or amikacin; beta-lactams (inhibition of cell wall synthesis) such as piperacillin, ticarcillin, 3rd and 4th generation cephalosporins (ceftazidime and cefepime), and carbapenems like imipenem or meropenem; or fluoroquinolones (ciprofloxacin) (interference with nucleic acid replication).
Based on previous testing performed using chlorine dioxide gas to successfully inactivate various Beta-Lactams, ClorDiSys Solutions, Inc.

Full browser ?