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 (bā′tə-lăk′tə-mās′, -māz′, bē′-)
Any of various enzymes that hydrolyze and inactivate beta-lactam antibiotics such as penicillin, found in many antibiotic-resistant bacteria.

[beta-lactam, cyclic amide occurring in penicillins (beta + lact(one) + am(ide)) + -ase.]
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Noun1.beta-lactamase - enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions


a. beta-lactamasa, enzima que destruye el conjunto de beta-lactam antibióticos penicílicos haciéndolos no efectivos;
beta-lactamase resistanceresistencia de beta-lactamasa, a algunos tipos de penicilina.
References in periodicals archive ?
Detection of plasmid-mediated AmpC betalactamase genes in clinical isolates by using multiplex PCR.
Crystal structure of extended-spectrum betalactamase Toho-1: insights into the molecular mechanism for catalytic reaction and substrate specificity expansion.
In this study Acinetobacter and Klebsiella resistance was due to production of betalactamase and carbapenemase which could highlight that Acinetobacter could be emerging as a multidrug resistant organism (XDR-AB), confirmed by the presence of the metallo-p-lactamase (MBL) and OXA genes.
The beta-lactamase inhibitors clavulanic acid and sulbactam are highly active in vitro against betalactamase producing strains [11].
Fatal endocarditis due to extended spectrum betalactamase producing Klebsiella terrigena in a liver transplant recipient," Wiener Klinische Wochenschrift, vol.
Mechanisms of resistance in Entrobacteriaceae towards betalactamase antibiotics.
The Staphylococcus aureus resistant to methicilin, the Pseudomonas aeruginosa the producer of the broadspectrum Betalactamase and the E.
A study of Extended spectrum betalactamase (ESBL) producers in clinical isolates.
Immunobiological role of llama heavy-chain antibodies against a bacterial betalactamase.
Horizontal dissemination of TEM- andSHV-type betalactamase genes carrying resistance plasmids amongst clinical isolates of Enterobacteriaceae.
Extended spectrum betalactamase production in Shigella isolates--a matter of concern.