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beta-lactamase
(redirected from Betalactamase)

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
be·ta-lac·ta·mase  (bt-lkt-ms, -mz, b-)
[beta-lactam, cyclic amide occurring in penicillins (beta + lact(one) + am(ide)) + -ase.]
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.beta-lactamase - enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions


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Despite sensitivity in vitro, all strains produced an inducible betalactamase.
Using amoxicillin-clavulanate in combination with ceftazidime, cefiriaxone, and aztreonam, we performed the double disk synergy test to determine whether this strain was an extended-spectrum betalactamase producer as described elsewhere (3); augmentation of the zone at the junction of amoxicillin-clavulanate and aztreonam/cefiriaxone/cefiazidime zones confirmed that indeed it was.
 
 
 
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