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Bextra

   Also found in: Medical, Wikipedia 0.01 sec.
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Noun1.Bextra - a Cox-2 inhibitor (trade name Bextra) that relieves pain and inflammation without harming the digestive tract
valdecoxib
Cox-2 inhibitor - an anti-inflammatory drug that fights pain and blocks Cox-2 activity without impeding the activity of Cox-1; increases the risk of heart attacks; "Cox-2 inhibitors reduce the symptoms of arthritis without endangering the stomach and kidneys"


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And physicians are becoming more leery of thinking that every new drug represents a 'breakthrough' or improvement over existing therapies--something that resulted in part from the problems around Vioxx and Bextra," she said.
Inside the medicine cabinet: health plans must decide whether to ... by Chordas, Lori / Best's Review
And it recommends a "black box warning"--the most serious possible--on the detailed package insert of all three Cox-2 drugs: Vioxx, Celebrex and Bextra.
Judge lets Vioxx lawyers discuss FDA memo by Curran, John / Los Angeles Business Journal
Based on this, Vioxx and Bextra may be associated with a higher risk of a heart attack because they are more potent inhibitors of COX-2 enzymes than Celebrex.
COX-2 inhibitors: what you need to know by National Women's Health Report
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