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bordetella |
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conorii, Legionella pneumophila, Bordetella pertussis, HIV, and human herpesviruses 1 and 2. Some researchers have been concerned that changes in the genetics of Bordetella pertussis, the most common pertussis-causing microbe, could underlie the disease's resurgence. Both the Chiron Biocine genetically engineered acellular pertussis vaccine and the chemically detoxified acellular pertussis vaccine in the Italian trial contain three Bordetella pertussis antigens: an inactivated form of pertussis toxin (PT), filamentous hemagglutinin (FHA) and pertactin (PRN -- an outer membrane protein), combined with diphtheria and tetanus toxoids. |
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