CD4


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CD4

 (sē′dē-fôr′)
n.
A glycoprotein that is found on the surface of T cells, especially helper T cells, and functions as a receptor in activation of the cells. In humans, HIV gains entry to helper T cells by binding to the CD4 receptor.

[c(luster of) d(ifferentiation antigen) 4.]

CD4


n.
a protein on the surface of T cells and other cells, functioning as a receptor for the AIDS virus antigen.
[1980–85; c(luster of) d(ifferentiation) 4]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.CD4 - a glycoprotein that is found primarily on the surface of helper T cells; "CD4 is a receptor for HIV in humans"
glycoprotein - a conjugated protein having a carbohydrate component
References in periodicals archive ?
VISITECT CD4, co-developed with the Burnet Institute, is the worlds first instrument-free and affordable rapid test for determining CD4 threshold in people living with HIV.
Widespread and routine use of CD4 counts and plasma viral load in the management of HIV has not been possible in resource limited settings.
Incomplete CD4 T cell recovery in HIV-1 infection after 12 months of highly active antiretroviral therapy is associated with ongoing increased CD4 T cell activation and turnover.
Key Words: Idiopathic CD4 Lymphocytopenia (ICL); Adrenal Histoplasmosis; Histoplasma Infection
2-5) Longer life with HIV depends on gaining CD4 cells and reaching an undetectable viral load.
CD4 T cell help is limiting and selective during the primary B cell response to influenza virus infection.
BD Biosciences disclosed on Thursday the availability of the CE-IVD marked BD FACSPresto Near Patient CD4 Counter system that provides absolute and percentage results of CD4 T lymphocytes and hemoglobin (Hb) concentration in whole blood samples to stage and monitor HIV/AIDS patients.
As the CD4 gene encodes its protein which participates in cellular immunity, its polymorphisms have been reported in correlation with different human diseases, including type 1 diabetes (Kristiansen et al.
HIV-1 binding to CD4 on CD4+ CD25+ regulatory T cells enhances their suppressive function and induces them to home to, and accumulate in, peripheral and mucosal lymphoid tissues: an additional mechanism of immunosuppression Int Immunol.
This is the first report of HIV negative patients with lymphocytopenia and CD4 lymphocytopenia with clinical immunodeficiency who did improve their T CD4 count, their lymphocytes count and their illness with anti-human herpes virus treatment.
The gold standard technique for CD4 enumeration is flow cytometry.