CD4 cell


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CD4 cell

n.
An activated helper T cell that expresses the CD4 receptor on its surface. Also called T4 cell.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.CD4 cell - T cell with CD4 receptor that recognizes antigens on the surface of a virus-infected cell and secretes lymphokines that stimulate B cells and killer T cells; helper T cells are infected and killed by the AIDS virus
T cell, T lymphocyte - a small lymphocyte developed in the thymus; it orchestrates the immune system's response to infected or malignant cells
References in periodicals archive ?
CD4 cell count-years, a total CD4 count over time defined in note 3
AZT-based antiretroviral therapy is associated with lower increases in CD4 cell counts than other HIV treatment regimens, according to a study published in the online edition of AIDS.
Two cases of HSIL+ were observed during the 5 years of observation, 1 among the HIV-uninfected women and 1 among the HIV-infected women with a CD4 cell count of 500 cells/uL or greater.
The analysis also showed that the risk for both hepatic failure and liver-related death increased at lower CD4 cell levels, and that treatment with anti-retroviral therapy did not worsen--and in some cases reduced--the rate of hepatic complications, Dr.
First-of-its-Kind Clinical Trial Measuring Bacillus coagulans Probiotics' Ability to Increase CD4 Cell Count in People with HIV Infection
Shortly after the HIV epidemic became established, it was a strongly held view that the only thing that mattered for understanding HIV pathogenicity was a falling CD4 cell count, as it was this that led to the opportunistic infections and ultimately to death.
An HIV- positive individual is generally given drugs only after his/ her CD4 cell count falls below 350 or he/ she starts developing symptoms of the disease.
2,3) In Europe 15 to 38 % of those infected with HIV do not present for testing until late in infection, with the UK sitting at the higher end of that bracket with 33% of all patients receiving their diagnosis when their CD4 cell count was less than 200/mm3, and/or disease progressed to clinical AIDS during the year of diagnosis.
In univariate analysis, the strongest predictors of mortality were a CD4 cell count <50/[micro]l (hazard ratio (HR) 3.
HIV-1 RNA concentrations and CD4 cell counts are moderately but inconsistently associated with parasitaemia.
The risk of infant death was reduced the higher the maternal CD4 cell count.
Costs among the sickest patients (those with the lowest CD4 cell counts) come to nearly triple those among individuals whose disease is least advanced.