CD8 cell

(redirected from CD8+ cell)
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Related to CD8+ cell: Cytotoxic T lymphocytes
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Noun1.CD8 cell - T cell with CD8 receptor that recognizes antigens on the surface of a virus-infected cell and binds to the infected cell and kill it
T cell, T lymphocyte - a small lymphocyte developed in the thymus; it orchestrates the immune system's response to infected or malignant cells
References in periodicals archive ?
Researchers measured CD4+ cell numbers, CD8+ cell numbers, and NK cell activity in all patients.
Age-related immune dysfunction in health and in human immunodeficiency virus (HIV) disease: association of age and HIV infection with naive CD8+ cell depletion, reduced expression of CD28 on CD8+ cells, and reduced thymic volumes.
This study has explored the effect of TGF-b on the ability of CD8+ cell to mediate a GVT effect against breast cancer cells.
Used to monitor the progression of HIV and alert physicians to the need for prophylactic drug therapies, the 4T8(R) assay measures CD4+ and CD8+ cell counts.
Biometric Imaging's IMAGN 2000(R) platform and its first application, the 4T8(TM) assay, have been cleared by the United States Food and Drug Administration (FDA) for CD4+ and CD8+ cell analysis and is used as a diagnostic for monitoring HIV progression.
Mice protected by Ampligen and/or a PD-1 inhibitor were resistant to rechallenge with viable melanoma cells in the absence of drug(s), indicating a memory effect, which is most likely mediated by anti-melanoma cytotoxic CD8+ cells.
After the treatment the number of CD8+ cells decreased more than 2 times.
It describes how previous adoptive immunotherapy using just CD8+ cells had shown no benefit and that cancer vaccines would have to elicit both CD4+ and CD8+ cells to be effective.
A protein produced by CD8+ cells of the adaptive immune system is exerting potent viral-suppressive activity through a mechanism thought to be reserved for cells of the innate immune system," said a co-author of the study.