inhibitor

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Related to COX-2 inhibitors: Prostaglandins

in·hib·i·tor

also in·hib·it·er  (ĭn-hĭb′ĭ-tər)
n.
One that inhibits, as a substance that retards or stops a chemical reaction.

inhibitor

(ɪnˈhɪbɪtə)
n
1. Also called: inhibiter a person or thing that inhibits
2. (Chemistry) Also called: anticatalyst a substance that retards or stops a chemical reaction. Compare catalyst
3. (Biochemistry) biochem
a. a substance that inhibits the action of an enzyme
b. a substance that inhibits a metabolic or physiological process: a plant growth inhibitor.
4. (General Physics) any impurity in a solid that prevents luminescence
5. (Astronautics) an inert substance added to some rocket fuels to inhibit ignition on certain surfaces

in•hib•i•tor

or in•hib•it•er

(ɪnˈhɪb ɪ tər)

n.
1. one that inhibits.
2. a substance that slows or stops a chemical reaction.
[1865–70]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.inhibitor - a substance that retards or stops an activity
substance - a particular kind or species of matter with uniform properties; "shigella is one of the most toxic substances known to man"
angiotensin II inhibitor - an agent that retards or restrains the action of angiotensin II
antioxidant - substance that inhibits oxidation or inhibits reactions promoted by oxygen or peroxides
anticatalyst - (chemistry) a substance that retards a chemical reaction or diminishes the activity of a catalyst
moderator - any substance used to slow down neutrons in nuclear reactors
activator - (biology) any agency bringing about activation; a molecule that increases the activity of an enzyme or a protein that increases the production of a gene product in DNA transcription
Translations

in·hib·i·tor

n. inhibidor, agente que causa una inhibición;
fusion ______ de fusión.

inhibitor

n inhibidor m; angiotensin converting enzyme — inhibidor de la enzima convertidora de angiotensina; cholinesterase — inhibidor de la colinesterasa; fusion — inhibidor de (la) fusión; integrase — inhibidor de la integrasa; monoamine oxidase — inhibidor de la monoaminooxidasa; non-nucleoside reverse transciptase — (NNRTI) inhibidor no nucleósido de la transcriptasa inversa or reversa; nucleoside reverse transcriptase — (NRTI) inhibidor nucleósido de la transcriptasa inversa or reversa; nucleotide reverse transcriptase — (NtRTI) inhibidor nucleótido de la transcriptasa inversa or reversa; protease — inhibidor de la proteasa; proton pump — inhibidor de la bomba de protones; selective serotonin reuptake — inhibidor selectivo de la recaptación de serotonina
References in periodicals archive ?
Although traditional NSAIDs inhibit both TXA[sub]2 and prostacyclin, selective COX-2 inhibitors do not affect TXA[sub]2 synthesis, due to the lack of COX-2 in platelets.
Although data from previous large studies suggest that high doses of NSAIDs as well as COX-2 inhibitors increase the risk of hospital admission for heart failure, "there is still limited information on the risk of heart failure associated with the use of individual NSAIDs in clinical practice," wrote Andrea Arfe of the University of Milano-Bicocca, Milan, and his colleagues (BMJ.
A recent analysis, published in the journal Rheumatology, found that the use of COX-2 inhibitors more than doubles the risk of venous thromboembolism (VTE)--the development of a blood clot in a deep vein that may then travels to the lung and form a pulmonary embolism.
The drugs evaluated by researchers were COX-2 inhibitors, which include celecoxib, rofecoxib, diclofenac, meloxicam, and etodolac, among others.
It is precisely for this reason that new COX-2 inhibitors, which block COX-2 "selectively," and not COX-1, zoomed into prominence.
With the introduction of the selective COX-2 inhibitors, it has been suggested that they may be more cost-effective because of their improved GI tolerability and a reduction in concomitant prescription of anti-ulcer agents.
7 times greater risk for falls and fractures than use of COX-2 inhibitors (Celebrex) and a 4.
Now experts writing in the British Medical Journal (BMJ) say the drugs together with a group of anti-inflammatories known as selective COX-2 inhibitors could increase the risk of abnormal heart rhythm.
The drugs include non-selective non-steroidal anti-inflammatory drugs (NSAIDS) as well as new generation anti-inflammatory drugs, known as selective COX-2 inhibitors.
70 percent more likely if they were on COX-2 inhibitors.
The primary goal of this paper was to determine what effect local and national television advertising on behalf of the two main COX-2 inhibitors had on the treatment decisions that patients made in collaboration with their physicians.