inhibitor

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Related to COX-2 inhibitors: Prostaglandins

in·hib·i·tor

also in·hib·it·er  (ĭn-hĭb′ĭ-tər)
n.
One that inhibits, as a substance that retards or stops a chemical reaction.

inhibitor

(ɪnˈhɪbɪtə)
n
1. Also called: inhibiter a person or thing that inhibits
2. (Chemistry) Also called: anticatalyst a substance that retards or stops a chemical reaction. Compare catalyst
3. (Biochemistry) biochem
a. a substance that inhibits the action of an enzyme
b. a substance that inhibits a metabolic or physiological process: a plant growth inhibitor.
4. (General Physics) any impurity in a solid that prevents luminescence
5. (Astronautics) an inert substance added to some rocket fuels to inhibit ignition on certain surfaces

in•hib•i•tor

or in•hib•it•er

(ɪnˈhɪb ɪ tər)

n.
1. one that inhibits.
2. a substance that slows or stops a chemical reaction.
[1865–70]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.inhibitor - a substance that retards or stops an activity
substance - a particular kind or species of matter with uniform properties; "shigella is one of the most toxic substances known to man"
angiotensin II inhibitor - an agent that retards or restrains the action of angiotensin II
antioxidant - substance that inhibits oxidation or inhibits reactions promoted by oxygen or peroxides
anticatalyst - (chemistry) a substance that retards a chemical reaction or diminishes the activity of a catalyst
moderator - any substance used to slow down neutrons in nuclear reactors
activator - (biology) any agency bringing about activation; a molecule that increases the activity of an enzyme or a protein that increases the production of a gene product in DNA transcription
Translations

in·hib·i·tor

n. inhibidor, agente que causa una inhibición;
fusion ______ de fusión.

inhibitor

n inhibidor m; angiotensin converting enzyme — inhibidor de la enzima convertidora de angiotensina; cholinesterase — inhibidor de la colinesterasa; fusion — inhibidor de (la) fusión; integrase — inhibidor de la integrasa; monoamine oxidase — inhibidor de la monoaminooxidasa; non-nucleoside reverse transciptase — (NNRTI) inhibidor no nucleósido de la transcriptasa inversa or reversa; nucleoside reverse transcriptase — (NRTI) inhibidor nucleósido de la transcriptasa inversa or reversa; nucleotide reverse transcriptase — (NtRTI) inhibidor nucleótido de la transcriptasa inversa or reversa; protease — inhibidor de la proteasa; proton pump — inhibidor de la bomba de protones; selective serotonin reuptake — inhibidor selectivo de la recaptación de serotonina
References in periodicals archive ?
The drugs evaluated by researchers were COX-2 inhibitors, which include celecoxib, rofecoxib, diclofenac, meloxicam, and etodolac, among others.
Now experts writing in the British Medical Journal (BMJ) say the drugs together with a group of anti-inflammatories known as selective COX-2 inhibitors could increase the risk of abnormal heart rhythm.
The drugs include non-selective non-steroidal anti-inflammatory drugs (NSAIDS) as well as new generation anti-inflammatory drugs, known as selective COX-2 inhibitors.
70 percent more likely if they were on COX-2 inhibitors.
The primary goal of this paper was to determine what effect local and national television advertising on behalf of the two main COX-2 inhibitors had on the treatment decisions that patients made in collaboration with their physicians.
Nonsteroidal antiinflammatory drugs (NSAIDs) are divided into two subcategories: (1) COX-2 specific inhibitors (referred to as COX-2 inhibitors for the remainder of this paper) such as celecoxib (Celebrex[R]), and (2) nonselective NSAIDs (referred to as NSAIDs for the remainder of this paper) such as ibuprofen (Motrin[R]).
The introduction of selective COX-2 inhibitors in the late 1990s substantially changed the arthritis treatment landscape because of the agents' ability to target the enzyme responsible for inflammation and pain while reducing the risk of NSAID-associated stomach complications, said Dr.
However, COX-2 inhibitors have been linked to a heightened risk of heart problems (SN: 10/30/04, p.
500) caution that 'there is now strong evidence to suggest that both the traditional NSAIDs (excluding aspirin) and the COX-2 inhibitors are associated with an increased risk of thrombotic events (including myocardial infarction and stroke) and excess mortality both in patients with and without pre-existing cardiovascular disease'.
Cox-2 inhibitors may increase the risk of heart attacks and strokes for patients taking high doses for long-term treatments, according to studies that led Merck & Co.
Celecoxib can be administered as palliative treatment to affected birds, but as with any nonsteroidal anti-inflammatory drug, COX-2 inhibitors should be used cautiously because they can adversely affect renal function by decreasing renal prostaglandin synthesis.