CREB


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Related to CREB: CREB binding protein

CREB

n
(Biochemistry) cyclic amp-response element binding protein; a protein involved in the long-term memory process
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sup][14] Membranes were probed with primary antibodies against CREB, phospho-Ser133-CREB (#9104 and #9191, respectively, Cell Signaling, USA), Arc , c-fos , and Egr1 (ab118929, ab53036, and ab55160, respectively, Abcam, USA).
Phosphorylation of CREB by p-ERK1/2 not only displays neuroprotection in stroke animals [36,41] but also prevents postischemic inflammation and neuronal damage [42].
The inhibition of nitric oxide synthase enhances PSA-NCAM expression and CREB phosphorylation in the rat hippocampus.
Quantitative RT-PCR was used to measure the expression of several of the genes found to be differentially expressed by RNA-Seq: the transcription factors Elk, FoxJ1, CREB (Fig.
Los niveles de CREB no aumentan en ratas que son re-expuestas al ambiente (el cual dejo de ser novedoso volviendose familiar), sino que los mismos descienden cuando el entrenamiento en el ambiente es prolongado (Winograd & Viola, 2004).
It was hypothesized that tolerance could be due to increased Ca 2+ entry into neurons, which then leads to Phosphorylation of CREB and transcription of pronociceptive gene like c-fos.
The induction of a transgene that expresses a dominant-negative member of the fly CREB family has specifically and completely blocked the formation of LTM in an olfactory task, whereas the induced expression of a dCREB2 activator isoform has enhanced it (Yin et al, 1994, 1995).
The expression of Bcl-2 can be induced by several promoters that bind to its regulatory region, including CREB (81).
Dan Borland, who has served as president of IPB since Opus's inception, has been promoted to president of CREB, and will also lead the structured-finance division.
The activation of these cascades, particularly the MAPK pathway, ultimately results in the recruitment and phosphorylation of two transcription factors, CREB and Elk-1, which in turn enhance the expression of a gene, activity-regulated cytoskeleton-associated (Arc) immediate-early gene, (1) (see figure 3) (Bramham et al.
2+], CaMKI, CREB, dendrites, developmental neurotoxicity, hippocampal MEK, neuronal connectivity, neurons, non-dioxin-like PCBs, ryanodine receptor, Wnt2.
CREB has been found to help fight addiction (SN: 5/24/08, p.