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active site
(redirected from Catalytic domain)

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
active site
n.
The part of an enzyme at which catalysis of the substrate occurs.

active site
The part of an enzyme where the catalytic activity on the substrate takes place. See more at enzyme.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.active site - the part of an enzyme or antibody where the chemical reaction occurs
site, situation - physical position in relation to the surroundings; "the sites are determined by highly specific sequences of nucleotides"
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
antibody - any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response


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The FHA domain is linked to the kinase/phosphatase catalytic domain by a flexible tether, and it exhibits a mode of target selection based on electrostatic complementarity between the binding surface and the phosphothreonine peptide.
Schering Corporation (Kenilworth, NJ) has patented a modified tumor necrosis factor-alpha converting enzyme catalytic domain, that unlike the native tumor necrosis factor-alpha converting enzyme catalytic domain, is stable at high protein concentrations.
Cysteine Residues in the Catalytic Domain of Furin are Essential for Catalytic Activity and Proper Subcellular Trafficking.
 
 
 
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