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Any of various enzymes found in animal tissue that catalyze the hydrolysis of proteins into smaller proteins.

[German Kathepsin, from Greek kathepsein, to digest : kat-, kata-, cata- + hepsein, to boil.]


(Biochemistry) a proteolytic enzyme responsible for the autolysis of cells after death
[C20: from Greek kathepsein to boil down, soften]


(kəˈθɛp sɪn)

any of a class of intracellular enzymes that break down protein in certain abnormal conditions and after death.
[1925–30; < Greek kathéps(ein) to digest]
ca•thep′tic (-tɪk) adj.
References in periodicals archive ?
com)-- AnaSpec is pleased to announce the release of two new SensoLyte[R] assay kits for the measurement of Cathepsin L activity - the SensoLyte[R] 520 and Rh110 Cathepsin L Assay Kits.
Hydrolysis of the FRET substrate by active Cathepsin L results in increase of HiLyte Fluor[TM] 488 fluorescence.
Its identified peptidic fraction preserves fibers of the elastic and collagen networks in the skin by favoring the synthesis of molecules involved in the organization of the fibril network (collagens, fibrillin) and also by limiting their degradation by enzymes such as MMP-1, -2 and cathepsin L.