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cell cycle
(redirected from Cell-cycle)

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
cell cycle
n.
The series of events involving the growth, replication, and division of a eukaryotic cell.

cell cycle
n
(Life Sciences & Allied Applications / Genetics) the growth cycle of eukaryotic cells. It is divided into five stages, known as G0, in which the cell is quiescent, G1 and G2, in which it increases in size, S, in which it duplicates its DNA, and M, in which it undergoes mitosis and divides


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The phenanthridine PJ-34 caused a permanent G2/M cell-cycle arrest and cell death within 48-72 hours in breast cancer MCF-7 and MDA231 cells.
These findings of a progressive decrease in Rb2/p130 expression from hyperplastic endometrium through atypical hyperplasia to poorly differentiated carcinomas suggest the involvement of this negative cell-cycle regulator in endometrial carcinogenesis.
Cell-cycle checkpoints are defined as mechanisms that regulate the cell cycle by monitoring key molecular processes involved and blocking their progression until these processes have been accurately completed.
 
 
 
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