sensitization

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sen·si·tize

 (sĕn′sĭ-tīz′)
v. sen·si·tized, sen·si·tiz·ing, sen·si·tiz·es
v.tr.
1. To make sensitive: "Solitude had sensitized him to the roughness of other people" (Jeffrey Eugenides).
2. To make (a film or plate) sensitive to light, especially to light of a specific wavelength.
3. To make hypersensitive or reactive to an antigen, such as pollen, especially by a second or repeated exposure.
v.intr.
To become sensitive or hypersensitive.


sen′si·ti·za′tion (-tĭ-zā′shən) n.
sen′si·tiz′er n.

sen•si•ti•za•tion

(ˌsɛn sɪ təˈzeɪ ʃən)

n.
1. the process of becoming susceptible to a given stimulus that previously had no effect or significance.
2. a state or condition in which a previously encountered foreign substance triggers an immune reaction.
[1885–90]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.sensitization - the state of being sensitive (as to an antigen)
irritation - (pathology) abnormal sensitivity to stimulation; "any food produced irritation of the stomach"
predisposition, sensitivity - susceptibility to a pathogen
2.sensitization - (psychology) the process of becoming highly sensitive to specific events or situations (especially emotional events or situations)
physical process, process - a sustained phenomenon or one marked by gradual changes through a series of states; "events now in process"; "the process of calcification begins later for boys than for girls"
psychological science, psychology - the science of mental life
3.sensitization - rendering an organism sensitive to a serum by a series of injections
immunisation, immunization - the act of making immune (especially by inoculation)
Translations

sen·si·ti·za·tion

n. sensibilización, acto de hacer sensible o sensorial.
References in periodicals archive ?
This scenario, they said, may set these patients up for visceral and central sensitization and present an increased risk for chronic pain.
As the affected cutaneous region was well-demarcated with its sensory innervation area and NCSs confirmed its axonal involvement, allodynia was regarded as a result of secondary central sensitization triggered by the disturbance of superficial peroneal nerve in this case, rather than a central pain secondary to thalamic involvement.
6] Like other chronic pain conditions, central sensitization may contribute to OA pain arising from chronic nociceptor stimulation and subsequent modification of central pain transmitting neurons.
Chronic pain conditions appear to fall into two categories: those that accompany identifiable illnesses like rheumatoid arthritis, neuropathy, and tumors, and those viewed as central sensitization or augmentation syndromes such as fibromyalgia and some other musculoskeletal pain conditions, pelvic pain, and some headaches.
For Florencio, central sensitization may explain the association between the frequency of migraine attacks and the severity of TMD.
This multimedia platform makes complex concepts easily digestible, such as the difference between central sensitization, long-term potentiation, and wind-up.
Central Sensitization and Sensitivity Syndromes: A Handbook for Coping
KEY WORDS: Brain-gut axis, Central sensitization, Irritable bowel syndrome, Migraine.
More likely in migraine, there is a form of central sensitization that may be classical central sensitization, or a form of dysinhibitory sensitization with dysfunction of descending modulatory pathways.
Central sensitization is the term used when this hypersensitivity develops in the superficial, deep, and ventral cord nerves.
The distortion and amplification of threat signals at the spinal cord and brain are termed central sensitization.
On a molecular level, central sensitization is associated with changes in the release of neuropeptides, neurotransmitters, and aspartate receptors in particular (70,71).

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