sensitization

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sen·si·tize

 (sĕn′sĭ-tīz′)
v. sen·si·tized, sen·si·tiz·ing, sen·si·tiz·es
v.tr.
1. To make sensitive: "Solitude had sensitized him to the roughness of other people" (Jeffrey Eugenides).
2. To make (a film or plate) sensitive to light, especially to light of a specific wavelength.
3. To make hypersensitive or reactive to an antigen, such as pollen, especially by a second or repeated exposure.
v.intr.
To become sensitive or hypersensitive.


sen′si·ti·za′tion (-tĭ-zā′shən) n.
sen′si·tiz′er n.

sen•si•ti•za•tion

(ˌsɛn sɪ təˈzeɪ ʃən)

n.
1. the process of becoming susceptible to a given stimulus that previously had no effect or significance.
2. a state or condition in which a previously encountered foreign substance triggers an immune reaction.
[1885–90]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.sensitization - the state of being sensitive (as to an antigen)
irritation - (pathology) abnormal sensitivity to stimulation; "any food produced irritation of the stomach"
predisposition, sensitivity - susceptibility to a pathogen
2.sensitization - (psychology) the process of becoming highly sensitive to specific events or situations (especially emotional events or situations)
physical process, process - a sustained phenomenon or one marked by gradual changes through a series of states; "events now in process"; "the process of calcification begins later for boys than for girls"
psychological science, psychology - the science of mental life
3.sensitization - rendering an organism sensitive to a serum by a series of injections
immunisation, immunization - the act of making immune (especially by inoculation)
Translations

sen·si·ti·za·tion

n. sensibilización, acto de hacer sensible o sensorial.
References in periodicals archive ?
TEHRAN (FNA)- Sleep disruption appears to be associated with altered pain processing and central sensitization, according to research.
Despite being mostly distributed in the early stages of development, first-in-class innovation is particularly concentrated on novel molecular targets that are aligned to the central sensitization associated with neuropathic pain, which is arguably the most debilitating and difficult-to-treat type of chronic pain.
Another aspect of central sensitization is the dysfunction in pain inhibition [8].
Additionally, NMDARs activate ERK via both PKA and PKC, which contributes to central sensitization through the cAMP response element-binding protein (CREB)-mediated transcriptional or non-transcriptional regulation (Ji et al.
Pain signals from the periphery ascend to the trigeminal nucleus caudalis in the brainstem, at which point central sensitization occurs.
Defining Classic Fibromyalgia: Central Sensitization
The hypothesis is that central sensitization as can be elicited by scar hyperalgesia after a previous cesarean section could result in increased pain if the surgery is repeated," she explained.
Those adolescents who have chronic daily headache and irritable bowel syndrome are at highest risk for central sensitization disorders such as fibromyalgia syndrome, chronic fatigue, and disturbed sleep.
4,12) During a central sensitization, some neurons may lose their tonic inhibition as they attempt to adapt, and they become disinhibited and overresponsive.
He calls them central sensitization syndromes, meaning patients are hypersensitive to any stimulus, not just pressure or touch but also noise, light and weather.
Pudendal neuralgia is multifactorial, involving not only compression of the nerve, for instance, but also muscle spasm and peripheral and central sensitization of pain.

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