Cerulenin


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Ce`ru`len´in


n.1.(Chem.) an antifungal antibiotic, C12H17NO3. It inhibits the growth of yeasts by interfering with the synthesis of sterols and fatty acids.
References in periodicals archive ?
Cerulenin was the first characterized FASN inhibitor derived from the fungus Cephalosporum caerulens (Omura 1976).
FAS inhibitor cerulenin reduces food intake and melanocortin receptor gene expression without modulating the other (an)orexigenic neuropeptides in chickens.
Fatty acid synthase inhibition with Cerulenin demonstrated a protective effect toward hepatic ischemia/reperfusion injury.