Among people randomized to the decision tree group, the greatest proportion received the nicotine patch (38%), followed by Chantix
(36%), nicotine patch plus lozenge (12%), bupropion (10%), or lozenge (4%).
Cytisine is a natural plant compound that works like the quit-smoking drug varenicline, marketed as Chantix
, by attaching to a protein receptor molecule on neurons.
Stout had claimed that McLaughlin overprescribed Chantix
- an anti-smoking drug whose potential side effects include depression and suicide - to her 49-year-old husband in an attempt to help him quit using tobacco.
Pfizer, which manufactures varenicline, a nicotinic receptor partial agonist in a tablet formulation, as Chantix
, is conducting the prospective, randomized, double-blind study comparing neuropsychiatric events in 8,000 smokers, with and without a psychiatric history, treated with varenicline, nicotine replacement therapy, bupropion, or placebo.
In the study, conducted by the manufacturer at the request of the FDA, major adverse cardiovascular events (MACEs), a composite endpoint of cardiovascular-related death, nonfatal MI, and nonfatal stroke, "were uncommon in both the Chantix
and placebo groups, and the increased risk was not statistically significant, which means it is uncertain whether the excess risk for the Chantix
group was due to the drug or due to chance," the FDA statement said.
In a new study, University of Chicago researchers found that varenicline, sold as Chantix
, increases the negative effects of alcohol.
The Food and Drug Administration (FDA) said Pfizer's anti-smoking drug called Chantix
needs to change its labeling in order to warn patients that using the medicine can slightly increase the risk of heart problems for those who already suffer from cardiovascular disease.
In addition, the Quit Line is reducing the monthly co-pay for Chantix
from $0 to $25 (for up to 3 months).
(Pfizer) is a best-selling smoking cessation drug.
The maker of cholesterol fighter Lipitor, impotence treatment Viagra and smoking drug Chantix
slashed costs on everything from manufacturing and marketing to research and development to produce net income of $2.
Nightmares and nausea are common side effects, but I generally find athletes and dancers tolerate Chantix
well," says Jackson.
The good news is that there are viable medical treatments to help you quit, like Zyban and Chantix