chemoattractant


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chemoattractant

(ˌkɛməʊəˈtræktənt)
n
(Biochemistry) a chemical substance that provokes chemotaxis, esp one that causes a bacterium to move in the direction in which its concentration is increasing
References in periodicals archive ?
DMT is further categorised into ACE inhibitors, ARBs, diuretics, calcium channel blockers (CCBs), renin inhibitors, connective tissue growth factor (CTGF) inhibitors, antioxidant inflammation modulators (AIMs), monocyte chemoattractant protein (MCP) inhibitors, endothelin-A receptor (ETAR) antagonist, G protein-coupled receptors (GPCRs), and others.
In addition, xanthoangelol (10, 25 or 50 [micro]M) and 4-hydroxyderricin (5, 10, 25 or 50 [micro]M) inhibited the production of IL-10 and monocyte chemoattractant protein (MCP)-l in M2-polarized macrophages.
The addition of a chemoattractant, such as betaine, taurine, glycine, or proline, to rearing water stimulates a vigorous search for food and leads to increased weight gain over time in Macrobrachium rosenbergii (Harpaz & Steiner 1990, Harpaz 1997).
Monocyte chemotactic protein-1 (MCP-1) acts as a chemoattractant, promoting infiltration of immune cells, and as a basophil agonist, which leads to histamine release.
Other chemoattractant receptors are also preferentially expressed on Th2 cells, including CCR4, CCR8, and CXCR4.
The expression of immunomodulatory membrane molecules such as inter-cellular adhesion molecule-1 (ICAM-1) by Western blot analysis, and the release of chemokines such as monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8) through ELISA kits, were determined.
Another mechanism involves chemoattractant substances, such as cytokines and growth factors, which can lead to an accumulation of dermal mast cells.
Urinary excretion of monocyte chemoattractant protein-1 in autosomal dominant polycystic kidney disease.
They found that a chemokine known as monocyte chemoattractant protein (MCP)-1 (CCL2) and its receptor, chemokine receptor 2 (CCR2), are central to the development of pain associated with knee OA.
11), (12) The cytokines interleukin (IL)-1beta, IL-6, and tumour necrosis factor (TNF) cooperate with the chemokines IL-8 (CXCL8) and monocyte chemoattractant protein (MCP-1, CCL2) to promote the transendothelial migration and chemotaxis of neutrophils and monocytes, facilitated by TLR-mediated release of histamine from tissue mast cells.
Comparative study of KL-6, surfactant protein-A, surfactant protein-D, and monocyte chemoattractant protein-1 as serum markers for interstitial lung diseases.
is a clinical-stage biopharmaceutical company focused on discovering, developing and commercializing orally-administered therapeutics that target the chemokine and chemoattractant systems in order to treat autoimmune diseases, inflammatory disorders and cancer.