Participants who received chromium picolinate
reduced their caloric intake by an average of 365 calories per day between their baseline and final (week 8) visit.
filed a petition before the Food and Drug Administration requesting that the agency allow the use of eight health claims associating chromium picolinate
supplementation with reduced risk of insulin resistance, type 2 diabetes and related conditions.
We gave either a placebo or 900 micrograms a day of chromium picolinate
to 35 overweight men and women between the ages of 54 and 71," says Wayne Campbell of Pennsylvania State University.
The company markets Chromax([R]) chromium picolinate
, which is the most-studied form of the essential mineral chromium.
The diets of test animals were supplemented with 400 mcg of chromium (lll) from ChromeMate or chromium picolinate
per kilogram of body weight.
The increases in glucose metabolism noted with both the active isomer and the combination of the isomer and chromium picolinate
were achieved in the absence of added insulin, and in each instance the level of glucose metabolism was greater than the level produced when insulin was added.
Ten rats that were fed extra chromium picolinate
throughout their lives lived 25 percent longer than 20 rats that were fed different forms of chromium.
In this study, investigators used Nutrition 21's proprietary chromium picolinate
found in Core4Life Advanced Memory Formula, a nutritional supplement specifically formulated to improve brain health.
Those individuals receiving chromium picolinate
plus biotin, in the form of Diachrome, also experienced a significant decrease in triglycerides to HDL ratio compared to the placebo group (p=0.
In fact, the researchers note that urinary chromium for chromium picolinate
was almost sixteen times higher than for chromium chloride, and over twice that of either of the two nicotinate-based forms.
Intlekofer concluded, "Our research on chromium picolinate
and several of our patented combinations have shown beneficial effects in lowering elevated blood sugar similar to current prescription medications.
In other news, the company has released results from a new clinical study that add to the growing body of clinical data demonstrating that daily supplementation with Diachrome, a combination of chromium picolinate
and biotin, can significantly reduce cardiovascular disease risk factors in people with type 2 diabetes.