Examples of autoimmunity diseases include celiac disease, diabetes mellitus type 1, sarcoidosis, systemic lupus erythematosus (SLE), Sj6gren's syndrome, Churg-Strauss syndrome, Hashimoto's thyroiditis, Graves' disease, idiopathic thrombocytopenic purpura, Addison's disease, rheumatoid arthritis (RA), polymyositis (PM), dermatomyositis (DM), pemphigus vulgaris, cicatricial pemphigoid
, multiple sclerosis, inflammatory bowel diseases (e.
Painful oropharyngeal lesions occur in granulomatosis with polyangiitis or Wegener granulomatosis, and autoimmune bullous diseases such as cicatricial pemphigoid
and pemphigus vulgaris.
Differential diagnosis for the bullous stage of bullous pemphigoid * Pemphigus vulgaris * Stevens-Johnson syndrome * Pseudoporphyria * Bullous drug eruption * Dermatitis herpetiformis * Paraneoplastic pemphigus * Bullous lupus erythematosus * Porphyria cutanea tarda * Bullous impetigo * Cicatricial pemphigoid
* Epidermolysis bullosa
This review focuses on the etiopathogenesis of main autoimmune bullous disorders including pemphigus, bullous pemphigoid, anti-p200 pemphigoid, cicatricial pemphigoid
, pemphigoid gestationis, dermatitis herpetiformis, linear IgA bullous dermatosis and epidermolysis bullosa acquisita.
Several studies18 have shown alterations in the expression of carbohydrates and mucin-associated molecules on the ocular surface of patients with ocular cicatricial pemphigoid
or other ocular surface diseases.
Lower on the list are other noninfectious causes of these symptoms, including lichen sclerosus, lupus erythematosus, cicatricial pemphigoid
, Stevens-Johnson syndrome, graft-versus-host disease, pemphigus of the mouth and skin, and a local drug reaction such as contact dermatitis.
1, Medicare will start covering IVIg treatments for certain mucocutaneous blistering diseases, including pemphigus vulgaris, pemphigus foliaceus, bullous pemphigoid, cicatricial pemphigoid
, and epidermolysis bullosa acquisita.
The procedure, performed at the San Raffaele Hospital in Milan, offers new hope to patients whose sight has been impaired by chemical burns, severe microbial infections, Stevens Johnson syndrome, or ocular cicatricial pemphigoid
The pemphigoid-group diseases consist of bullous pemphigoid, childhood bullous pemphigoid, localised bullous pemphigoid, drug-induced pemphigoid, anti p200 pemphigoid, pemphigoid gestationes, pemphigoid nodularis, and cicatricial pemphigoid
The diagnosis of anogenital lichen sclerosus can usually be made clinically; however, several inflammatory dermatoses can occur in the anogenital area: lichen planus, cicatricial pemphigoid
, lichen simplex, morphea, and eczema.
The differential diagnosis included Behcet's disease, cicatricial pemphigoid
, a fixed drug reaction, and allergic contact dermatitis.
She said it does not scar except in vulvovaginal areas, where it can lead to disfigurements similar to cicatricial pemphigoid