Cinnoline, quinoxaline, and pthalazine (Figure-1) are the structural isomers of quinazoline.
Ravina, Synthesis and Biological Evaluation of New Quinazoline and Cinnoline Derivatives as Potential Atypical Antipsychotics, Chem.
(99) was surely formed, based on the result that the enehydrazine part attacked the root of the MsO group in a nucleophilic manner, followed by an aromatic addition-elimination reaction but not cyclization, as shown by the intermediate 100.
These alkaloids include quinazoline, quinaxaline, cinnoline
, phthalazine and other three or four membered ring azaheterocycles such as, pteridine, alloxazine, isoalloxazine .
In order to circumvent these issues, a novel two-step synthetic method to prepare benzoic] cinnoline
18 and its chlorinated derivatives 19-22 as well as dibenzo[c,h]cinnolines
23-24 is proposed.
3:30 SYNTHESIS AND CHARACTERIZATION OF OLIGO- BENZO[c] CINNOLINE
ETHYNYLENES AS MOLECULAR JUNCTIONS**, Bridgette Sands', Danielle Mitchell and Gillslain Manclouma
3:30 SYNTHESIS AND CHARACTERIZATION OF OLIGO-BENZO[c] CINNOLINE
ETHYNYLENES AS MOLECULAR JUNCTIONS**, Briclgette Sands*, Danielle Mitchell and Ghislain Manclouma, Albany State University, Albany, GA 31705.
4-dichloronitrobenzene 1 followed by Wilcox diazotization of 2, 2'-dinitro-5, 5'-dichlorobiphenyl 2 and a selective nitration of 2, 7-dichlorobenzo[c] cinnoline
The second supplement updates Simpson's 1953 and Singerman and Patel's 1973 publications in this series by surveying the literature on both cinnolines
and phthalazines published from 1972 through 2004, an impressive feat (1041 references are cited).
The book contains six chapters covering synthesis, reactions and applications in the following subject areas: pyridazines, cinnolines
, benzocinnolines and phthalazines; pyrimidines and quinazolines; pyrazines and related ring structures; phenzine, oxazine, thiazine and sulphur dyes; quinazoline alkaloids; six-membered rings with three or more hetero-atoms.